Polymalic acid-based nanodrugs: Anti-tumor efficacy and host compatibility
Black K.L., Ding Hui, Dobrovolskaia M.A., Gangulum P., Holler E., Inoue S., Ljubimova J.Y., McNeil S.E., Patil R., Patri A., Portilla J., Cedars-Sinai Medical Center, US
A polyanionic drug carriers is presented that penetrates biobarriers and targets molecular cancer markers of human breast and brain cancer. The carrier platform is poly(beta-L-malic acid) (PMLA), which is highly water soluble and biodegradable to [...]