Discriminated properties of PEI functionalized gold nanoparticles (Au-PEIs) predetermined by synthetic routes of ligand exchange and reduction processes: Paths and Fates

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Polyethyleneimine (PEI) functionalized AuNPs (Au-PEIs) have potential use as positively charged gold nanoparticles (AuNPs) for nano-medicinal applications, due to their cationic surfaces that promote cellular uptake and gene transfection.1-6 Au-PEIs can be prepared by one [...]

Supramolecular assemblies of cisplatin and polyelectrolytes: preparation, characterization and activity against cancer cells

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Nanoformulation of cisplatin (Cis) is important to circumvent its high toxicity against normal cells. In this work, Cis cationic nanoparticles were prepared by the self-assembly of drug and oppositely charged polyelectrolytes (carboxymethylcellulose, CMC; chitosan, CH; [...]