nanoparticles – Page 12 – TechConnect Briefs

Iron-oxide nanoparticle synthesis from liquid spray flames under variable pressure conditions

Hardt S., Wiggers H., Wlokas I., Kempf A., Schulz C., University of Duisburg-Essen, DE

Iron-oxide nanoparticles have been synthesized via liquid-fed flame spray pyrolysis (FSP) under variable pressure conditions. The work focuses on the effect of pressure, precursor flow rate, and flame stoichiometry on particle size, composition, and morphology. [...]

A Novel Pulsed High-density Plasma Process for Nanoparticle Synthesis

Helmersson U., Söderström D., Pilch I., Pillay S., Brenning N., Linkoping University, SE

Today there are various plasma techniques where material is sputtered and used to synthesize nanoparticles. However, we have been unable to identify anyone ionizing the sputtered material in such a process. The advantage of ionizing [...]

Pilot-scale Nanoparticle Manufacture

Wegner K., Grohn A., Multer S., ETH Zürich, CH

A fully automated pilot plant for nanoparticle manufacture by flame spray pyrolysis is presented that allows continuous production of nanopowders at rates up to 500 g/h. For the example of zirconia the scale-up from the [...]

Polymer Coated Nickel Ferrite Nanoparticles for High-gradient Magnetic Separation

Alvarez R., Trad T.M., Martirosyan K.S., University of Texas at Brownsville, US

Magnetic separation is a complex physical process in which magnetically susceptible composites is extracted from a liquid mixture using magnetic properties of the substances. Several separation procedures are developed based on magnetic susceptibility, magnetohydrostatic, magnetohydrodynamic [...]

Polymer Coated Nickel Ferrite Nanoparticles for High-gradient Magnetic Separation

Alvarez R., Trad T.M., Martirosyan K.S., University of Texas at Brownsville, US

Magnetic separation is a complex physical process in which magnetically susceptible composites is extracted from a liquid mixture using magnetic properties of the substances. Several separation procedures are developed based on magnetic susceptibility, magnetohydrostatic, magnetohydrodynamic [...]

Assessment of comparative toxicity of nano- and microparticles of magnetite

Katsnelson B.A., Privalova L.I., Degtyareva T.D., Kuzmin S.V., Sutunkova M.P., Minigalieva I.A., Kireyeva E.P., Khodos M.Y., Shur V.Y., Nikolaeva E.V., Valamina I.E., Tulakina L.G., Pichugova S.V., Beykin J.B., Federal State Institution of Sciences Medical Research, RU

Assessment of toxicity of 10 nm, 50 nm and 1 um Fe3O4 particles based on shift in the cell population of the broncho-alveolar lavage fluid after their intratracheal instillation into lungs of rats and on [...]

Sulfur-33 Nanoparticles: A Possible Target for Neutron Capture Therapy of Cancer

Porras I., University of Granada, ES

Sulfur nanoparticles, enriched in the isotope S-33 are potential neutron capturers for enhancing neutron radiation dose in tumors, because of a nuclear reaction of this isotope which produces a high energy alpha particle which delivers [...]

Overcome the Doxorubicin Resistance by Multimodal Nanoparticles in Mice

Lai P.S., Hsu C.Y., Lu H.-L., Yu H.-P., Syu W.-J., Shieh M.J., National Chung Hsing University, TW

The efficacy of many chemotherapeutic agents is reduced in cells that have developed multiple drug resistance (MDR). To address this important problem, a biodegradable polymer was coupled to the photosensitizer and the resulting photosensitizer-nanoparticles were [...]

The Effect of Anticancer Nanotherapy on Lewis Lung Carcinoma

Orel V.E., Shevchenko A.D., Nikolov N.A., Dzyatkovskya N.N., Romanov A.V., Richalskiy A.Yu., Burlaka A.P., Lukin S.M., Uvarov V.N., Schepotin I.B., National Cancer Institute, UA

Introduction. Current forms of antitumor anthracycline antibiotic doxorubicin (DOXO) are highly toxic to the patient and can cause systematic complications, most notably cardiotoxicity. Systemic toxicity can seriously decrease the effectiveness of the drug since a [...]

New High Conductance DEP Devices for Detection of Cancer Related DNA Nanoparticulate Biomarkers and Nanoparticles in Whole Blood

Heller M.J., Sonnenberg A., University of California San Diego, US

The ability to rapidly detect cell free circulating (cfc) DNA nanoparticulate biomarkers, drug delivery nanoparticles and virus directly from blood is a major challenge for nanomedicine. We have now developed unique, simple and practical high [...]