nanoparticles – Page 10 – TechConnect Briefs

Multifunctional plasmonic nanoparticles for biomedical applications

Sotiriou G.A., Pratsinis S.E., ETH Zürich, CH

Plasmonic nanoparticles play an important role in biomedical applications today as they can serve as superior optically-stable bioimaging agents, be employed in biosensor devices for the early diagnosis of diseases, and exhibit promising results for [...]

Polymerization Passivation Strategies for the Stabilization of Energetic Aluminum Nanomaterials

Jelliss P.A., Thomas B.J., Patel A., Lloyd E., Guliants E.A., Bunker C.E., Buckner S.W., Saint Louis University, US

We are developing aluminum nanoparticle (Al NP) passivation strategies based on our established protocols for polymerization of epoxide molecules with a view to fabricating air-stable Al NPs with long shelf-lives. Additionally we have discovered that [...]

The influence of technique on the measured particle size distribution of complex nanoparticle systems

Jämting Å.K., Roy M., Catchpoole H.J., Lawn M., Babic B., Coleman V.A., Herrmann J., National Measurement Institute Australia, AU

Accurate and reliable characterization of nanoparticles is crucial for both industrial applica-tions and studies of their toxicological and environmental impacts. Particle size distribution (PSD) has been widely recognised as one of the key parameters that [...]

Effects of ZnO buffer layer and depth profiling analysis of bulk heterojunction organic solar cells

Mbule P.S., Kim B.S., Kim T-H., Kim B.S., Kim T-H., Swart H.C., Ntwaeaborwa O.M., University of the Free State, ZA

Bulk heterojunction organic solar cells (BHJs) with ZnO nanoparticles buffer layer between the active layer and the aluminum (Al) top electrode were fabricated. The BHJs comprised of successive layers of poly(3,4ethylenedioxythiophene):poly(styrenesulfonate) (PEDOT:PSS), a blend of [...]

Magnetic properties of metallic AuPdO nanoparticles confined in ordered mesoporous silica SBA-15 channels

Iwamoto W., Lesseux G.G., Dias B.F., Teixeira-Neto A.A., Teixeira-Neto E., Teixeira-Neto A.A., Teixeira-Neto E., Urbano R.R., Rettori C., Universidade Estadual de Campinas (UNICAMP), BR

Materials consisting of metallic AuPdO nanoparticles (AuPdO-NPs) supported on mesoporous silica SBA-15 channels (AuPdO-NPs/SBA15, Figure 1) have become composite compounds of great interest due to their catalytic applications [1]. In this work we report on [...]

Ultrastructure of hepatic cells in rabbits after injection of nanoparticles MCS-B

Belousov A.N., Laboratory Applied Nanotechnology, UA

In order to determine ultrastructural reconstructions in hepatic cells under effect of nanoparticles of magnetite (MCS-B), an experiment was conducted on 45 rabbits. Ultrastructural changes in hepatocyte organelles manifested pronounced signs of activation of reparative [...]

Encapsulation and Characterization of BSA in PLA-PEG Nanoparticles as a Model for Chlamydia trachomatis rMOMP-278 Protein Nanovaccine Delivery System

Taha M., Singh S.R., Moore C., Agee R., Dennis V.A., Alabama State University, US

Chlamydia trachomatis is a major human health pathogen because it is the most reported sexually transmitted disease. There is no effective mucosal vaccine against Chlamydia. One of the major problems of the C.trachomatis vaccine development [...]

In vitro anticancer activity of poly(3-hydroxybutyrate) nanoparticles loaded with antitumor drug Paclitaxel

Yakovlev S.G., Bonartsev A.P., Bonartseva G.A., Bagrov D.V., Efremov Yu.M., Boskhomdzhiev A.P., Filatova E.V., Ivanov P.V., Makhina T.K., Bonartseva G.A., A.N.Bach’s Institute of Biochemistry Russian Academy of Sciences, RU

We have produced nanoparticles loaded with antitumor drug paclitaxel. Operated nanospheres were prepared on the base of a biodegradable and biocompatible polymer of bacterial origin, poly(3-hydroxybutyrate) (PHB). PHB nanoparticles with paclitaxel (230±55 nm in diameter) [...]

Orally Delivered Polymeric nanoparticles of Lopinavir: Development and Statistical optimization, in vitro and ex vivo studies

Joshi G., Sawant K.K., M S University of Baroda, IN

Nanoparticles (NPs) have been extensively studied for oral drug delivery. NPs are taken up intact by M cells of peyer’s patches of gut associated lymphoid tissue (GALT) followed by its systemic circulation thereby preventing first [...]

Supramolecular assemblies of cisplatin and polyelectrolytes: preparation, characterization and activity against cancer cells

Vieira D.B., Kim V., Petri D.F.S., Menck C.F.M., Carmona-Ribeiro A.M., Universidade de Sao Paulo, BR

Nanoformulation of cisplatin (Cis) is important to circumvent its high toxicity against normal cells. In this work, Cis cationic nanoparticles were prepared by the self-assembly of drug and oppositely charged polyelectrolytes (carboxymethylcellulose, CMC; chitosan, CH; [...]