microfluidics – Page 12 – TechConnect Briefs

The Model of Porous Media – Complete Description for Aggregation of Bead-Monolayers in Flat Microfluidic Chambers

Grumann M., Dobmeier M., Schippers P., Brenner T., Zengerle R., Ducrée J., IMTEK, University of Freiburg, DE

In this paper we for the first time adopt the model of porous media to simulate the complete course of the formation of monolayers from bead suspensions in a flat microfluidic chamber. The chambers are [...]

Taylor Dispersion in Electroosmotic Flows with Random Zeta Potentials

Gleeson J.P., Stone H.A., University College Cork, IE

Electroosmotic flows are extensively employed for fluid transport and sample separation in lab-on-a-chip technologies, capillary zone electrophoresis, and generally in channels and capillaries with length scales on the order of 100 microns or less. Experimental [...]

Circuit Modeling and Simulation of Integrated Microfluidic Systems

Chatterjee A.N., Aluru N.R., Beckman Institute, US

A combined circuit-device model for the analysis of integrated microfluidic system is presented. The complete model of an integrated microfluidic device incorporates modeling of the fluidic transport, chemical reaction, reagent mixing and separation. The microfluidic [...]

Lattice Boltzmann Simulations Comparing Conventional and a Heat Conduction Based Flow-Through PCR Micro-Devices

Mautner T., SPAWAR Systems Center San Diego, US

This paper describes the lattice Boltzmann, numerical simu-lations used to evaluate a conduction-based, polymerase chain reaction (PCR) device for uniformity of the micro channel temperature profile and its velocity field distribu-tion. For comparison purposes, numerical [...]

Flow Simulation of a Microfluidic Analog of the Four-Roll Mill

Phelan_Jr. F.R., Hudson S.D., NIST, US

The fluid dynamics of geometries for liquid state materials characterization in microfluidic devices are investigated. A pressure driven device using microchannels is sought that has an adjustable flow type, approximating the function of the four-roll [...]

Polymeric Micropump with SU-8 Check Valves Assembled by Lamination Technique

Truong T-Q, Nguyen N-T., Nanyang Technological University, SG

This paper presents the first micropumps assembled using polymeric lamination technology. Each pump consists of two 100-m-thick, 10-mm-diameter SU-8 discs; two 1.5-mm-thick, 15-mm-diameter polymethylmethacrylate (PMMA) discs; and one piezo disc. The SU-8 parts were fabricated [...]

Dielectrophoresis (DEP) of Cells and Microparticle in PDMS Microfluidic Channels

Kanagasabapathi T.T., Backhouse C.J., Kaler K.V.I.S., University of Calgary, CA

Dielectrophoresis (DEP) [1] The behavior of polarized, neutral particles to the non-uniform electric field has been successfully applied for the levitation and subsequent isolation of biological cells and other micron-sized inorganic particles [2, 3]. This [...]

Sample-Shunting Based PCR Microfluidic Device

Auroux P-A, Day P.J.R., Manz A., Imperial College, UK

A new method to perform on-chip DNA amplification is presented in this abstract: we shunt the sample back and forth over temperature-controlled zones. Compared to existing systems, this approach offers, in addition to a greater [...]

Development of a Slug-Flow PCR Chip with Minimum Heating Cycle Times

Hardt S., Dadic D., Doffing F., Drese K.S., Münchow G., Sörensen O., Institute of Microtechnology Mainz, DE

A microfluidic PCR device is presented capable of rapid temperature ramping and handling of sample volumes in the microliter and submicroliter range. The PCR chip comprises a straight micro channel in which a sample slug [...]

A Numerical Model of Viscoelastic Flows in Microchannels

Trebotich D., Colella P., Miller G., Liepmann D., Lawrence Livermore National Laboratory, US

We present a numerical method to model non-Newtonian, viscoelastic flow at the microscale. The equations of motion are the incompressible Navier-Stokes equations coupled with the Oldroyd-B constitutive equation. This constitutive equation is chosen to model [...]