Lattice Boltzmann Simulations Comparing Conventional and a Heat Conduction Based Flow-Through PCR Micro-Devices


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This paper describes the lattice Boltzmann, numerical simu-lations used to evaluate a conduction-based, polymerase chain reaction (PCR) device for uniformity of the micro channel temperature profile and its velocity field distribu-tion. For comparison purposes, numerical simulations were also performed using conventional PCR configurations. The simulation results demonstrate that in two-dimensions adequate performance of both the conventional and the heat conduction-based PCR systems. However, three-dimensional results indicate that nearly uniform wall tem-peratures (top, bottom and sides) are required to obtain uni-form temperature fields in the PCR micro channels.

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Journal: TechConnect Briefs
Volume: 1, Technical Proceedings of the 2004 NSTI Nanotechnology Conference and Trade Show, Volume 1
Published: March 7, 2004
Pages: 328 - 331
Industry sectors: Advanced Materials & Manufacturing | Sensors, MEMS, Electronics
Topic: MEMS & NEMS Devices, Modeling & Applications
ISBN: 0-9728422-7-6