lab-on-chip – TechConnect Briefs

Nanoscale Flow Chip Platform For Laboratory Evaluation Of Enhanced Oil Recovery Materials

Engel M., Neumann R.F., Giro R., Bryant P.W., Steiner M.B., IBM Research Brazil, BR

We present a lab-on-chip platform for the experimental evaluation of Enhanced Oil Recovery [EOR] methods from the nanoscale to the scale of reservoir rock pore networks. We have employed semiconductor process technology to build lab-on-chip [...]

System for Measuring Drop Volume and Consistency in Lab-on-Chip Applications

Kipman Y., Mehta P., ImageXpert Inc., US

A machine vision based system has been developed for measuring in-channel characteristics of droplets for lab-on-chip microfluidic applications. The small, fully integrated system can be used in R&D and in production and combines a high-powered [...]

Lab-on-chip for the isolation and characterization of circulating tumor cells

Laureyn W., Liu C., O’Sullivan C.K., Llaudet E., Nilsson O., Drese K.S., Roeser T., Ritzi M., Hauch S., Albert W., Borgen E., Nygren A.O.H., IMEC, BE

A consortium of 7 European partners has undertaken the challenging task to develop a microfluidic system (μTAS) capable of the isolation/enrichment and consecutive RNA/DNA characterization of circulating tumor cells (CTCs), to be used as a [...]

Fast and Efficient Nucleic Acid Testing by ST‘s In-CheckTM Lab-on-Chip Platform

Conoci S., Di Francesco F., Di Pietro P., Di Trapani G., Petralia S., Amore M.G., San Biagio F., Alaimo G., Iacono G., Alessi E., Ricceri D., Di Francesco F., Di Pietro P., Di Trapani G., Di Francesco F., Di Pietro P., Di Trapani G., Palmieri M., STMicroelectronics, IT

Nucleic Acid Testing (NAT) represents one the most sensitive and effective method for several applications in the molecular diagnostic area, including clinical, industrial, veterinary and research applications. In this context, the development of miniaturized devices [...]

Direct-Write CMOS-Based Laboratory-On-Chip

Ghafar-Zadeh E., Sawan M., Therriault D., École Polytechnique de Montréal, CA

Over the recent years, the identification of genes which influence many diseases has been highly demanded and now, molecular diagnosis is most promising technology to offer fast and early detection of diseases to a maximum [...]

Surface modification and characterization of a cyclic olefin copolymer for magnetic bead-based stop-flow microfluidic ELISA

Herrmann M., Veres T., Tabrizian M., McGill University, CA

This abstract describes a microfluidic platform for simple, highly effective and parallel Enzyme Linked Immuno-Sorbent Assay (ELISA). The method is based on the use of magnetic micro-beads in order to increase the capture rate of [...]

Modular Design Approaches for MicroFluidic Systems

Gilde M.J., van den Vlekkert H., Leeuwis H., Prak A., CapiliX BV, NL

The possibilities promised by microfluidic systems have not only interested scientists, but also industries, especially in the areas of the Life Sciences (food, medical, biotech) and fine chemistry (pharma) [2]. Microfluidics is the MEMS-field in [...]

Investigation of Volume of Fluids (VOF) Method and System Models for Design of Microfluidic Ink Delivery Apparatus for Dip Pen Nanolithography (DPN)

Banerjee D., Texas A&M University, US

DPN™ is a versatile technology that leverages Scanning Probe Microscopy for applications in biotechnology, photomask repair, molecular-electronics, nano-electronics and mask-less lithography(1). In earlier studies (2) the DPN process was augmented for biotechnology applications (genomics, proteomics) [...]

A Computational Model for the Design of ElectroWetting On Dielectric (EWOD) Systems

Bedekar A.S., Jenkins J.W., Sundaram S., CFD Research Corporation, US

Microfluidics has enabled the development of integrated lab-on-a-chip (LoC) devices for use in a clinical diagnostics, high throughput screening, drug discovery, biodefense and environmental monitoring. Although most microfluidic devices are based on continuous flow of [...]