Fluorescence – Page 4 – TechConnect Briefs

A Fluorescence Spectroscopy Study on the Encapsulation of Hydrophobic Dyes in Core-Shell Nanoparticles

Chavez J.L., Wong J.L., Duran R.S., University of Florida, US

Novel core-shell nanoparticles were prepared as encapsulating agents for fluorescent organic dyes. These particles protect the dyes from polar solvents, allowing their use in aqueous environments, such as biological systems. The nanoparticles were synthesized using [...]

Neuroimaging Distribution of Water Molecules in Brain

Vaganova E., Yitzchaik S., Ovadia H., Borst J.W., Visser A., Sigalov M., Khodorkovsky V., The Hebrew University, IL

We were able to elucidate and build the map of the water molecules distribution in a brain tissue in hippocampus/lateral vetricle area by means of the injected chromophore bis-N-carbazolyl-distyrylbenzene (BND) and FLIM technique. The BND [...]

Surface modification and characterization of a cyclic olefin copolymer for magnetic bead-based stop-flow microfluidic ELISA

Herrmann M., Veres T., Tabrizian M., McGill University, CA

This abstract describes a microfluidic platform for simple, highly effective and parallel Enzyme Linked Immuno-Sorbent Assay (ELISA). The method is based on the use of magnetic micro-beads in order to increase the capture rate of [...]

PCR-free DNA-based biosensing with polymeric optical hybridization transduction using micro- and submicron-magnetic bead captured on micro-electromagnetic traps

Dubus S., Le Droggof B., Gravel J-F., Boudreau D., Veres T., Laval University, CA

DNA-based biosensor technologies for rapid, sensitive and affordable identification of genetic material are in constant evolution and show great potential in various fields. The ability for such methods to be used directly at point-of-care settings [...]

Dendrimer Nanoparticles for Extending Biosensor Lifetime

Qian X., Tabacco M.B., Smiths Detection, US

Smiths Detection has been developing semi-selective optical biosensors for the direct airborne detection of the four primary classes of biological warfare agent: bacteria, bacterial spores, toxins and viruses. The sensors have good sensitivity and selectivity. [...]

A Droplet Microarray for Homogeneous Enzymatic Assay

Balakirev M., Mugherli L., Chatelain F., CEA-Grenoble, FR

This work describes a droplet microarray for monitoring of enzymatic activity on a glass slide. These array are composed of features defined and separated by differential surface tension (surface tension array). A photolithographic method was [...]

Modeling Image Formation in Layered Structures: Application to X-ray Lithography

Bollepalli S.B., Khan M., Cerrina F., UW-Madison, US

In the fabrication of semiconductor devices using lithography, the modeling of the exposure process is very often needed. The elements of a typical exposure system from a modeling perspective comprise of a radiation source, a [...]