The biodegradable polymeric PLA-PEG nanoparticles is an efficient delivery system for a chlamydial M278 mucosal nanovaccine that provides protective systemic and mucosal antibody responses in mice

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The rising concerns relating to the failure of public health programs, relying mostly on antibiotic treatments to control the plethora of disease manifestations caused by Chlamydia trachomatis in humans, strongly begs the urgency for an [...]

Nanoconjugates of poly(malic acid) with functional modules for drug delivery

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Nanoconjugates of β-poly(L-malic acid) (PMLA) have been synthesized with modules active in drug delivery, drug release, blocking of tumor-affiliated mRNA by antisense oligonucleotides, penetration of blood and cellular barriers, tissue targeting, membrane permeation, fluorescence, and [...]