Kim T.I. – TechConnect Briefs

The characterization and reductive degradation behavior study of bioreducible crosslinked polypropylenimine dendrimers for gene delivery systems

Lee G.J., Ryu K., Kim T.I., Seoul National University, KR

Polypropylenimine (PPI) dendrimers and their derivatives have been used for gene delivery because of their properties such as cationic charge, equivalent surface functionalities, and internal cavities [1–4]. However, high generation PPIs made high cytotoxicity induced [...]

Self-assembling peptide dimers with multifunctionalities for gene delivery systems

Ryu K., Lee G.J., Kim T.I., Seoul National University, KR

Peptides have been used in various biomedical fields including gene and drug delivery systems [1]. There are many peptide sequences which can interact with cellular molecules or components. These biological interactions of peptide represented many [...]

Biological effects of PLA-TCP nanocomposites on osteoblastic cells

Kim H.W., Kim J.W., Kim T.I., Lee H.-H., Lee S.-P., Kim H.W., Kim J.W., Kim T.I., Kim H.W., Kim J.W., Kim T.I., Lee H.-H., Lee S.-P., Seoul National University, KR

Composite substrates are considered as prospective matrix to populate and support cells in the bioengineering field. Synthetic degradable biomaterials, including poly(lactic acid) (PLA) and tricalcium phosphate (TCP), are widely used for matrix scaffold. In present [...]

Biological influence of nanofibrous hydroxyapatite-polycaprolactone membrane on human periodontal ligament cell

Kim H.W., Kim T.I., Lee S.J., Ku Y., Rhyu I.C., Chung C.P., Han S.B., Kim H.W., Kim T.I., Seoul National University, KR

This study was performed to evaluate the effect of hydroxyapatite-coated nanofibrous polycaprolactone membrane on proliferation and differentiation of periodontal ligament cell which is necessary for periodontal regeneration. Hydroxyapatite-coated nanofibrous polycaprolactone membrane was fabricated through electrospinning [...]