Chen Z.J. – TechConnect Briefs

Multiscale Design of a Laser Actuated Micro Bubble Array Acoustic-Fluidic Microdevice for Bioanalytical and Drug Delivery Applications

Chen Z.J., Przekwas A.J., CFD Research Corporation, US

Next generation fluidic micro-nano devices will require precise control of force fields within a device and their interaction with a biological sample. Current force field designs use mechanical structures such as cantilevers, optical fields e.g. [...]

Solving Electric Field in Combined Conductor and Dielectric Devices

Chen Z.J., Przekwas A., Athavale M., Zhou N., CFD Research Coorporation, US

In the design and simulation of micro/nano device areas, it becomes more and more important to obtain, fast and accurate, transient electric field solutions in combined conductor/dielectric materials. The time characteristics for such transient process [...]

Numerical and Analytical Studies of AC Electric Field in Dielectrophoretic Electrode Arrays

Feng J.J., Krishnamoorthy S., Chen Z.J., Makhijani V.B., CFD Research Corporation, US

Manipulation of micro-sized particles and biological cells using dielectrophoresis (DEP) is an emerging technique in MEMS and nano technology[3]. This paper presents an exact solution of dielectrophoretic motion of a polarized particle in the vicinity [...]

Numerical and Analytical Studies of AC Electric Field in Dielectrophoretic Electrode Arrays

Feng J.J., Krishnamoorthy S., Chen Z.J., Makhijani V.B., CFD Research Corporation, US

Manipulation of micro-sized particles and biological cells using dielectrophoresis (DEP) is an emerging technique in MEMS and nano technology[3]. This paper presents an exact solution of dielectrophoretic motion of a polarized particle in the vicinity [...]

Coupled Multiphysics and Chemistry Simulations of PCR Microreactors with Active Control

Athavale M.M., Chen Z.J., Furmanczyk M., Przekwas A.J., CFD Research Corporation, US

High-fidelity simulation tools that couple fluid flow, heat transfer and chemistry of PCR microreactors have been applied to different microreactor designs. The tools are coupled to a controller software for thermal control of the virtual [...]

Electrodynamic Transport, Electroporation and Lysis of Cells in Pharmacological and Bioanalytical Microsystems

Przekwas A.J., Chen Z.J., Athavale M., CFD Research Corporation, US

Biological information is stored in cells and is the prime object of interest of pharmacological, biomedical, and bioanalytical professionals. Whatever the interest: elcectroporative drug delivery and pharmacodynamics, in vivo PCR, infection pathology, DN