Boisseau P. – TechConnect Briefs

Development and Validation of Characterization Methods for Lipidots® Multifunctional Platform: a Step forward Industrial Transfer

Varache M., Ciancone M., Caputo F., Laffont C., Escudé M., Jary D., Boisseau P., Texier I., Navarro F.P., Couffin A.C., CEA-LETI, FR

For eight years, our research group has been developing lipid nanocarriers, known as Lipidots®, as a multifunctional platform for medical applications. A wide range of active pharmaceutical ingredients (APIs) and contrast imaging agents has been [...]

Lipid nanoparticles: tumor-targeting nanocargos for drug and contrast agent delivery

Delmas T., Navarro F., Gravier J., Thomann J.S., Heinrich E., Mérian J., Fraichard A., Boisgard R., Tavitian B., Dufort S., Coll J.L., Bibette J., Boisseau P., Couffin A.C., Texier I., CEA-Grenoble, FR

A new technology for the encapsulation of lipophilic molecules -both drugs and contrast agents dedicated to chemotherapy, phototherapy, or fluorescence imaging in oncology- has been developed, based on oil-in-water nanoemulsions. Thorough physico-chemical characterizations of the [...]