National Taiwan University – TechConnect Briefs

Gold Nanoshells With Micellar Core for The Delivery of Hydrophobic Chemotherapeutic and Cancer Photothermal Therapy

Lee S-Y, Shieh M.J., National Taiwan University, TW

Gold nanoshells have attracted great research interest because of its potential application in cancer photothermal therapy. In the present study, we established a multifunctional gold nanoshell that directly utilizing positively charged PDMA-b-PCL micelles as a [...]

An inkjet printed NO2 sensor operating under room temperature and low humidity environment

Wang W., Su Y-C, Chuang W-Y, Lin C-T, Wu W-J, National Taiwan University, TW

A room temperature operation NO2 sensor base on polypyrrole (PPy) /AZO (5% Al-doped ZnO) sensing material was developed. For the environmental monitoring, the ambient factor effect for NO2 detection was further discussed. Based on the [...]

Synthesis of amphiphilic block copolymers to deliver HSP90 inhibitors for colorectal tumors

Lin C.Y., Shieh M.J., National Taiwan University, TW

In this article, we present pH-sensitive and small size nanoparticles as carrier to encapsulate 17-AAG. We anticipate that this platform will provide a new strategy for cancer therapy.

Novel Photo-thermal Controlled Drug-releasing Vectors for Cancer Detection and Treatment

Tsai M-H, Ling D., Shieh M.J., National Taiwan University, TW

Cancer is always the leading cause of deaths in worldwide. The aim of this research is to develop a new generation of chemotherapeutic drugs with both photothermal activated drug release and MRI diagnostic function. Carbon [...]

Multi-functional micelles for the combination of chemotherapy and radiotherapy in hepatocellular carcinoma

Shih Y-H, Peng C.L., Luo T-Y, Shieh M.J., National Taiwan University, TW

Hepatocellular carcinoma is the third leading cause of cancer deaths in worldwide. In this study, multi-functional micelles loaded with doxorubicin (Dox) and labeled with the radionuclide rhenium-188 (188Re) were developed to provide the combination of [...]

Enhanced Cell Electro-permeabilisation Combined with Phototherapy to Target-Killing Cancer Cells by Using Multi Functional Carbon Nanotubes

Lee P-C, National Taiwan University, TW

Carbon nanotubes (CNTs) have been proposed and actively explored as multifunctional innovative carriers for drug delivery. This project presents a new modality for cell electro-permeabilisation based on the use of CNTs and external static electric [...]

A Pressure Sensor Array with Sensing Ragnes Tunable by Drving Frequency

Lai Y.-T., Yang Y-J, National Taiwan University, TW

This work presents the development of a novel pressure sensing array which sensing ranges are tunable during operation. The sensing element consists of carbon nanotubes (CNT) dispersed in nematic liquid crystals composites. The sensing ranges [...]

Numerical simulation of binary droplet collision using CFD software tools

Pan K.L., Liao M.W., National Taiwan University, TW

The dynamics of head-on collision between two identical droplets was computationally investigated using a commercialized volume-of-fluid (VOF) method. The results were compared to that obtained by a front-tracking method and experiments. The simulated collision images [...]

Preparation and Application of Copper Oxide Nanoparticles

Chang M-H, Tai C.Y-D, National Taiwan University, TW

The aim of this research was to synthesize copper oxide (CuO) nanoparticles, which were further applied to prepare CuO-water nanofluid, using a spinning disk reactor (SDR). The precursor of copper oxide was first synthesized by [...]

Ultrasensitive Protein Detection Using an Au/ZnO SPR-Based Biosensor

Chang C-C, Lin C-W, Lin S-H, Chiu N.-F., Lin C-W, Lin S-H, National Taiwan University, TW

In this study, we demonstrated that the Au/ZnO nanocomposite films could be effectively used to enhance the performance of SPR for the detection of tumor marker. Carbohydrate antigen 15.3 (CA15.3) tumor marker for breast cancer [...]