Alabama State University – Page 4

Encapsulation and in vitro characterization of protein in PLGA-chitosan nanoparticles for efficient protein delivery

Subbarayan P., Dennis V.A., Lee C., Nyairo E., Singh S.R., Alabama State University, US

Respiratory Syncytial Virus (RSV) is one of the most common causes of severe respiratory tract infections affecting mainly elderly, infants and the immunocompromised worldwide. As yet, a safe and effective vaccine has not been developed [...]

Characterization of rMOMP-187 Peptide Encapsulated in PLGA 50:50 Nanoparticles

Taha M., Singh S.R., Butler C., Nyairo E., Dennis V.A., Alabama State University, US

The design of an immunization regimen capable of inducing sustained genital mucosal Th1 response is the current goal for a vaccine for humans to control the severe complications of genital infection by C. trachomatis. In [...]

CNT and Silver-CNT Nanoparticles provide immune responses against RSV

Boyoglu C., Boyoglu S., Adiani L., Boyoglu C., Boyoglu S., Mishra M., Rangari V., Dennis V., Singh S.R., Alabama State University, US

Nanobiotechnology and its potential to be used in treating and diagnosing general and viral infections have allowed us to step into a new realm, when dealing with Respiratory synctical virus (RSV). RSV has long been [...]

Antimicrobial properties of silver coated CNT

Ashour D., Subbarayan P., Adiani L., Boyoglu S., Mohammad G., Rangari V., Jeelani S., Ram Singh S., Pillai S., Alabama State University, US

Surface microbial infestation of biomedical devices such as catheters, prosthetics, and implants can result in serious infection and device failure. Surface-centered infections are also implicated in food spoilage, and spread of food-borne diseases. Hence, there [...]

Inhibitory Effects of Gold and Silver Nanoparticles on RSV Studied by Atomic Force

Boyoglu S., Vig K., Pfendt A., Pillai S., Willing G.A., Singh S.R., Alabama State University, US

Human Respiratory Syncytial Virus (RSV) causes severe lower respiratory tract infections in infants which may progress to pneumonia. RSV accounts for approximately 4,500 deaths and 90,000 hospitalizations in infants and children in the United States [...]

Silver Coated Carbon Nanotubes Inhibit RSV Infection

Adiani L., Subbarayan P., Boyoglu S., Vig K., Pillai S., Rangari V., Singh S.R., Alabama State University, US

Respiratory Syncytial Virus (RSV) is a member of the genus Pneumovirus in the family of Paramyxoviridae. It is one of the most common causes of upper and lower respiratory tract infections, bronchiolitis and pneumonia worldwide [...]

Respiratory Syncytial Virus Inhibition by Gold and Titanium Nanoparticles

Vig K., Boyoglu S., Rangari V., Pillai S., Singh S.R., Alabama State University, US

Respiratory Syncytial Virus (RSV) is the leading cause of severe respiratory illnesses including bronchiolitis and pneumonia in young children. The RSV surface proteins F (fusion) and G (attachment) are major targets for vaccine development against [...]

Evaluation of Nanoencapsulated DNA Vaccine for RSV

Boyoglu S., Vig K., Rangari V., Pillai S., Dennis V., Singh S.R., Alabama State University, US

Polymer nanoparticles have been used as carriers to enhance drug delivery. Among them chitosan is the most commonly used carrier, because it promotes long term of incorporated drugs. In the present study,we used DNA vaccine [...]

Use of Nanoparticles as Therapy for Respiratory Syncytial Virus Inhibition

Vig K., Boyoglu S., Rangari V., Sun L., Singh A., Singh S.R., Pillai S., Singh A., Singh S.R., Alabama State University, US

Respiratory Syncytial Virus is the leading cause of severe respiratory illnesses such as bronchiolitis and pneumonia in young children. RSV is a paramyxovirus with negative-sense genomic RNA that encodes for eleven proteins, two of which, [...]