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Building and Testing Scalable Fuzzy Models of Genetic Regulation in Bacteria

Sokhansanj B.A., Rodrigue G.R., Fitch J.P., Lawrence Livermore National Laboratory, US
Recent technological advances in high-throughput data collection (reviewed in [1]) give biologists the ability to study increasingly complex systems as a whole. One example is the DNA chip or microarray, an efficient high-throughput method for [...]

Complex Fluid Dynamics in BioMEMS Devices: Modeling of Microfabricated Microneedles

Liepmann D., University of California-Berkeley, US
MEMS technologies promises to revolutionize health care by providing precise control of biological fluids for both diagnoses and treatments. For example, microneedles can be used for sample collection for biological analysis, delivery of cell or [...]

What to do with Statistical Mechanics when the Figure of Merit Cannot be Calculated: Library Design for High-Throughput Materials Development

Deem M.W., University of California, Los Angeles, US
By analogy with Monte Carlo algorithms, we discuss new strategies for design and redesign of libraries in high-throughput experimentation, or combinatorial chemistry. Several Monte Carlo methods are examined, including Metropolis, several types of biased schemes, [...]

The Inverse Band Structure Approach: Given the desired electronic property, find the atomic configuration

Zunger A., National Renewable Energy Laboratory, US
Modern crystal-growth techniques, such as molecular beam epitaxy or metal-organic chemical-vapour deposition, are capable of producing prescribed crystal structures, sometimes even in defiance of equilibrium, bulk thermodynamics. These techniques open up the possibility of exploring [...]

The Number of Human Genes and Proteins

Davison D., Bristol-Myers Squibb, Pharmaceutical Research Institute, US
The definitive prototype for nanotechnology is the cell. Its many machines and exquisitely controlled internal and external movements are a reference for all researchers working in the field. The complete instructions for every molecular machine [...]

The Vision and Action Plan of the National Nanotechnology Initiative

Roco M., National Science Foundation, US
The vision of novel phenomena, unity in nature, and promise of the most efficient manufacturing length scale has been essential in establishing the multidisciplinary National Nanotechnology Initiative (NNI). The research opportunities and projections of their [...]

Measurements and Modeling of Mobility in Ultra-Thin SOI

Mastrapasqua M., Esseni D., Fiegna C., Agere Systems, US
We present a study of the effective mobility (ueff) of ultra thin SOI n MOSFETs for both single and double gate operation. Electron mobility was measured for silicon thickness Tsi down to approximately 5 nm [...]

Methodology for Model Generation with Accuracy from DC to RF

Zhang X., Williams M., Liu Z., Celestry Design Technologies, US
This paper presents an example modeling flow for generating a RF CMOS model. Initially, the objectives of this modeling approach are analyzed. Then issues in test structure design are discussed. In the section of model [...]

How to Build an SOI MOSFET Compact Model without Violating the Laws of Physics

Watts J., IBM Microelectronics, US
An important application for partially depleted SOI is high performance microprocessors and other logic chips. In order to deliver market leading performance it is necessary for transistor design and circuit design to be done concurrently. [...]

The Role of TCAD in Compact Modeling

Duane M., Applied Materials, US
This paper is an introduction to semiconductor process and device simulation and its role in compact modeling for circuit simulation. A brief history of TCAD is given. One use of TCAD is in the generation [...]

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