TW – Page 34 – TechConnect Briefs

Calculating Deflection of Micro-Cantilever with Self-Assembled Monolayer Molecules Using Molecular Dynamics Simulations

Kan H-C, Wang Y-T, Tsai S-H, National Center for High-performance Computing, TW

Self-assembled Monolayers (SAM) by spontaneous adsorption of molecules on microscale substrates have attracted a huge interest due to their scientific importance and potential uses in technological applications and health care industry. Diverse selections of SAM [...]

Amorphous Diamond Electron Emission for Thermal Generation of Electricity

Sung E., Sung J.C-M, Sung M., Kan K., Sung E., Sung J.C-M, Sung M., Huang J-L, Sung E., Sung J.C-M, Sung M., Chen C-P, Hsu K-H, Tai M-F, Kinik Company, TW

Amorphous diamond represents a class of material of its own. It may be viewed to be a composite of metal (graphite) and insulator (diamond), but together they form a unique passage for electrons to flow [...]

Investigation of Molecular Rearrangement by AFM Analysis of SAMs Annealing Process

Wu C-L, Hsieh H-Y, Tseng F-G, Chieng C-C, National Tsing Hua University, TW

Self assembly monolayers (SAMs) are easily prepared nano-film, and have been widely applied to improve device surface properties and biomaterial conjugation on substrates. Among various steps, annealing is one of the general processes for the [...]

Sample Concentration by Asymmetry EOF flow in Micro/Nano Channels with O2/H2O Plasma Treated Channel Surfaces

Wu R-Q, Tseng F-G, Yang C-S, Cheing C-C, National Tsing Hua University, TW

In this study, we propose a new technique to concentrate sample effectively, which employs different surface treatment on the top and bottom of micro/nano channels. This treatment carries out different zeta-potentials on the opposite walls [...]

Computational Modeling and Simulation of Microfluidic Biochips for Parallel Biomolecular Synthesis

Kan H-C, National Center for High-performance Computing, TW

In this study, a novel microfluidics based biochip has been developed by the aid of analytical modeling and numerical simulation efforts for the purpose of massively parallel oligonucleotude-DNA (oDNA) syntheses. The microfluidic biochip consists of [...]

Electrokinetic and Hydrodynamic Focusing/Switching in Microfluidics

Yang R-J, Chang C-C, Huang S-B, Lee G-B, National Cheng Kung University, TW

This paper presents an investigation on hydrodynamic/electrokinetic focusing and switching, which are crucial for microfluidic applications. The hydrodynamic/electrokinetic focusing phenomenon is first theoretically modeled by employing a potential flow theory, and this simple theoretical model [...]

Detecting Drug Screen by Acoustic Wave Sensor

Shih C-J, Ke W-W, Lieu C-H, ITRI, TW

The Severe Acute Respiratory Syndrome (SARS) is induced to the patients pervasively pneumonia and respired exhaustion. In previously study (2), the nucleic acid 318 and 510 of S protein was the crucial fragments to bind [...]

Temperature Uniformity and DNA Amplification Efficiency in Micromachined Glass PCR Chip

Huang C-C, Wang M., Liu W-P, Weng K-Y, Yao L-Y, Industrial Technology Research Institute, TW

We have fabricated glass-based micromachined DNA polymerase chain reaction (PCR) chips with different heater patterns. Two pieces of Pyrex 7740 glass are thermally bonded together to form the PCR reaction channel. The PCR channel was [...]

Enhancement of E6 Protein Binding on Binding-Orientation-Sensitive Mixed SAMs Molecules

Tseng F-G, Tseng Y.T., Hwang J.K., Hung S.W., Chang J.M., Huang H.M., Huang T.W., Tseng F-G, Tseng Y.T., Huang H.M., Huang T.W., Chieng C-C, National Tsing Hua University, TW

Orientation selectivity and binding enhancement with E6 protein are demonstrated by nano-structured mixed-SAMs systems of different chain lengths. Mixtures of n-alkinethiol SAMs of different chain lengths: 1-Decanethiol (C9) and 1-Hexanethiol (C5) are the examples in [...]

The Use of Quartz Crystal Microbalance in Cell Differentiation Detection

Shih C-J, Ke W-W, Lieu C-H, Industrial Technology Research Institute/Electronics Research & Service Organization, TW

We try to investigate whether the hematopoietic cell differentiation can be detected by Quartz Crystal Microbalance. Because certain hematopoietic transcription factors play a critical role in cell differentiation and lineage determination, they can be alternate [...]