IT – Page 12 – TechConnect Briefs

New Process for Production of Bio-Diesel from Vegetable Oil

Caputo G., Giaconia A., Sau S., Felici C., Lanchi M., Tarquini P., ENEA, IT

NEW PROCESS FOR PRODUCTION OF BIO-DIESEL FROM VEGETABLE OIL Low-cost, high-capacity processes for the conversion of biomass into fuels and chemicals are essential for expanding the utilization of carbon neutral processes, reducing dependency on fossil [...]

Halloysite Clay Nanotubes: Characterization, Biocompatibility and Use as Drug Carriers

Vergaro V., Abdullayev E., Zeitoun A., Giovinazzo G., Santino A., Cingolani R., Lvov Y.M., Leporatti S., National Nanotechnology Laboratory (NNL) of CNR-INFM, IT

Halloysite nanotubes (HNTs) are efficient nano-containers capable of entrapping a range of active agents within the inner lumen, followed by their retention and slow release. Halloysite is a green environmentally friendly object available in commercial [...]

Nanocarriers for Cancer Therapy

Vergaro V., Zheng X., Zheng Z., Zheng X., Zheng Z., Lvov Y.M., Giovinazzo G., Santino A., Cingolani R., Rinaldi R., Leporatti S., National Nanotechnology Laboratory (NNL) of CNR-INFM, IT

Drug nano-colloids encapsulated by combination of layer by layer (LbL) techniques and ultrasonication, phytochemical encapsulated-artificial oleosomes and drug-loading clay nanotubes have been uptaken by neoplastic cells. Morpho- mechanical changes induced by such nanocarriers in living [...]

A novel stem cell tag-less sorting method

Roda B., Lanzoni G., Alviano F., Zattoni A., Costa R., Di Carlo A., Marchionni C., Franchina M., Ricci F., Tazzari P., Pagliaro P., Scalinci S.Z., Bonsi L., Reschiglian P., Bagnara G.P., University of Bologna, IT

New methods for stem cells isolation are being developed. Common procedures for stem cell sorting involve flow cytometry which makes use of fluorescent or magnetic tags to isolate and separate cells which are phenotypically different. [...]

A tag-less method for the direct isolation of HUVEC (human umbilical vein endothelial cells) by gravitational field-flow fractionation as a starting point for gene expression analysis

Lattuada D., Roda B., Pignatari C., Magni R., Cattaneo A., Bolis G., Reschiglian P., University of Bologna, IT

HUVECs (human umbilical vein endothelial cells) are a model for prediction of endothelial dysfunction in various diseases. HUVECs are enzymatically removed from the umbilical vein by collagenase. This method allows for a good sample yield, [...]

Analysis and characterization of multifunctional oligothiophene-silica hybrid nanomaterials by AF4-MALS-Fl

Rambaldi D.C., Zattoni A., Reschiglian P., Melucci M., Zambianchi M., Barbarella G., Bonacchi S., Montalti M., Rampazzo E., University of Bologna, IT

We present results indicating that Asymmetrical Flow Field-Flow Fractionation (AF4) on-line coupled with Multi-Angle Light Scattering (MALS) and Fluorescence (FD) detection can become the unparallel methodology for morphological and optical characterization of new, structured, fluorescent [...]

Hollow-fiber flow field-flow fractionation: a novel pre-MS method for proteomics

Rambaldi D., Zattoni A., Reschiglian P., Johann C., University of Bologna, IT

It is well acknowledged that both number and dynamic range of the proteins present in biological systems lead to the need of a “simplified” and more efficient way to proteome analysis. The availability of so-called [...]

A flow-assisted point-of-care testing device based on gravitational field-flow fractionation for analysis on biological fluids

Mirasoli M., Cevenini L., Casolari S., Roda A., Roda B., Di Carlo A., Reschiglian P., Roda A., Roda B., University of Bologna, IT

The “Point-Of-Care Testing” (POCT) approach is based on the development of portable analytical platforms suitable to perform analysis directly in any required place. A POCT device should combine portability, minimum sample pre-treatment, and the possibility [...]

Electrochemiluminescent sensor for clinical analysis based on Carbon Nanotube electrodes

Sanginario A., Demarchi D., Giorcelli M., Castellino M., Politecnico di Torino, IT

Presented application is based on the use of carbon nanotubes (CNTs) for biomolecular analysis using electrochemiluminescence (ECL) detection technique. For this purpose we have grown self standing cylinder-shaped blocks of Multi wall CNTs (MWCNTs) by [...]

Synchrotron radiation microtomography for the ex-vivo and in-vivo evaluation of nanoparticle-labeled stem cell homing in muscular tissue

Fiori F., Farini A., Giuliani A., Manescu A., Villa C., Torrente Y., Polytechnic University of Marche, IT

This work was carried out in the frame of a more general research program aiming to use human stem cells to repair muscle damage in Duchenne Muscular Dystrophy. The results of X-ray microtomography experiments, carried [...]