Developing nanoscale probes capable of real-time sensing and imaging of neuronal action potentials would be useful in understanding neuronal communication. However, current available tools for imaging action potentials lack either the spatial or temporal sensitivity [...]
Fluorescence continues to be one of the most useful tools employed by life scientists to visualize cellular processes. Semiconductor nanocrystals or quantum dots (QDs) have been demonstrated to be superior alternatives to traditional fluorophores (dyes [...]
This work presents SU-8 based Flexure-FET biosensor to achieve ultrasensitive response. Here, gate of FET is replaced with the fixed-fixed beam. Beam is biased near to pull-in instability (Vpi) and FET channel is biased in [...]
The sensitivity of a designed electrochemical DNA biosensor was improved using gold and or silver nanoparticles. A gold electrode modified with a conductive nanocomposite of poly(3,4-ethylenedioxythiophen)–poly(styrenesulfonate) (Pedot-Pss) and gold or silver nanoparticles enhanced the conductivity [...]
Since gold nanoparticle (AuNP)-based colorimetric assays have been preferred for enzyme activity assay, a few of attempts have been designed for the simple and rapid detection of PP activity. However, they still have drawbacks including [...]
Colorimetric detection of glucose in sample liquids such as human plasma is made by using enzymatic reactions. In the multi reactional scheme, the first enzymatic reaction is determinant. Either glucose oxidase (GOX) or glucose dehydrogenase [...]
SU-8 is a popular epoxy based negative photoresist developed by IBM. It has been widely used as structural material in Bio-MEMS and Lab-on-a-Chip devices due to its bio-compatible properties. SU-8 surface has hydrophobic nature. Often [...]
We have mounted 5 different biocatalysts on a sensor platform to examine the performance of this electrochemical sensing system for the detection of different biomolecules/metabolites and environmental important molecules, with such we also compared how [...]
Herein we report a fluorescent nanosensor base on magnetic silica nanoparticle as illicit drug logic gate. A novel naphthlimide derivative was synthesized (F) , characterized and doped into the magnetic silica nanoparticles (Fe3O4@SiO2-F). Herein we [...]
The NIEHS sets aside a percentage of extramural funds to support technology development for environmental health research through Small Business Innovation Research (SBIR) and Small Business Technology Transfer (STTR) grants. SBIR/STTR technologies supported by NIEHS [...]
Cyanide is an important industrial chemical but is also very toxic. Cyanide binds strongly with hemoglobin than that of oxygen which causes histoxic hypoxia, if cyanide is ingested into the bloodstream. This pairing reaction can [...]
In this work, we evaluated relationship between specific contact resistance and sensitivity of pH sensor by changing the ohmic contact metallization consisted of source and drain. The sample was fabricated for analysis of electrical characteristics [...]
The "chemical nose/tongue" approach presents a potential alternative to specific recognition and separations techniques. In this approach a sensor array is generated to provide differential interaction with analytes via selective receptors, generating a stimulus response [...]
Nanosensors employing quantum dots (QDs) and functional moieties such as enzymes are promising for diagnostics and chemical/biological threat activity. Their small size permits cell penetration and their inherent photochemical properties are well-suited for rapid, optical [...]
An optical device (multilayer optical strip, MOS) is presented. It is composed of a small-sized, strip-shaped, multilayer, planar structure connected to a control unit. Active and passive optical elements allow for controlling the properties, spatial [...]
Amyloid-beta (A) plaque accumulation in the brain has been recognized to be associated with Alzheimer’s and dementia. Challenges of quantitation of Ab are the instability of soluble Ab1-42 and the protein interference plus the time [...]
The technology developed is an in-situ measurement system for monitoring the performance of piezoelectronic sensors, particularly accelerometers. With this technology, characteristics such as resonant frequency, response, cable status, connectivity, bonding and linear range, can be [...]
For the several decades, various nanomaterials are broadly used in industrial fields, research areas and commercialized products. Among many nanomaterials, silver ion, carbon nanotube, ZnO, and mercury ion etc are of the widely used nanomaterial [...]
The aim of this work was to contribute to the development of a simple and cheap biomimetic sensor, providing a higher sensitivity and selectivity toward microbiological contaminations. An optimization of the matrix of the optical [...]
, Kanakia S.
, Khan S.
, Kukarni P.
, Lee S.
, Moore W.
, Shroyer K.
, Sitharaman B.
, Toussaint J.
, Stony Brook University, US
Contrast-enhanced magnetic resonance angiography (MRA) employs the use of blood pool contrast agents (CA) such as gadolinium (Gd3+) complexes that allow for delayed phase arterial and venous imaging and improve the sensitivity in detecting small [...]
Journal: TechConnect Briefs
Volume: 3, Biotech, Biomaterials and Biomedical: TechConnect Briefs 2015
Published: June 14, 2015
Industry sectors: Medical & Biotech | Sensors, MEMS, Electronics
Topic: Sensors - Chemical, Physical & Bio