Papers:
Sensing voltage change across a lipid bilayer
Chen Y., Makinen A.J., O’Shaughnessy T.J., Efros A.L., Huston A., Susumu K., Stewart M.H., Delehanty J.B., Naval Research Laboratory, US
Developing nanoscale probes capable of real-time sensing and imaging of neuronal action potentials would be useful in understanding neuronal communication. However, current available tools for imaging action potentials lack either the spatial or temporal sensitivity [...]
Cellular Delivery Modalities for Semiconductor Quantum Dots: A Comparative Analysis
Fluorescence continues to be one of the most useful tools employed by life scientists to visualize cellular processes. Semiconductor nanocrystals or quantum dots (QDs) have been demonstrated to be superior alternatives to traditional fluorophores (dyes [...]
SU-8 Based Flexure-FET Biosensor to Achieve Ultrasensitive Response
This work presents SU-8 based Flexure-FET biosensor to achieve ultrasensitive response. Here, gate of FET is replaced with the fixed-fixed beam. Beam is biased near to pull-in instability (Vpi) and FET channel is biased in [...]
Improving the sensitivity of Pedot:Pss modified gold electrode using gold and silver nanoparticles for Ganoderma boninense DNA detection
The sensitivity of a designed electrochemical DNA biosensor was improved using gold and or silver nanoparticles. A gold electrode modified with a conductive nanocomposite of poly(3,4-ethylenedioxythiophen)–poly(styrenesulfonate) (Pedot-Pss) and gold or silver nanoparticles enhanced the conductivity [...]
Zn(II)-Mediated Gold Nanosensors for Protein Phosphatase Assay
Since gold nanoparticle (AuNP)-based colorimetric assays have been preferred for enzyme activity assay,[1] a few of attempts have been designed for the simple and rapid detection of PP activity. However, they still have drawbacks including [...]
Determination of the bi-substrate kinetic coefficients for the beta-D-glucose- NAD-GDH enzymatic reaction
Colorimetric detection of glucose in sample liquids such as human plasma is made by using enzymatic reactions. In the multi reactional scheme, the first enzymatic reaction is determinant. Either glucose oxidase (GOX) or glucose dehydrogenase [...]
A simple process for selective bio-functionalization of SU-8 surface for Lab-on-a-Chip applications
SU-8 is a popular epoxy based negative photoresist developed by IBM. It has been widely used as structural material in Bio-MEMS and Lab-on-a-Chip devices due to its bio-compatible properties. SU-8 surface has hydrophobic nature. Often [...]
Comprehensive Analysis of High Performing Electrochemical Biosensors and Their Applications
We have mounted 5 different biocatalysts on a sensor platform to examine the performance of this electrochemical sensing system for the detection of different biomolecules/metabolites and environmental important molecules, with such we also compared how [...]
A fluorescent nanosensor base on magnetic silica nanoparticles as illicit drug vapor logic gate
Herein we report a fluorescent nanosensor base on magnetic silica nanoparticle as illicit drug logic gate. A novel naphthlimide derivative was synthesized (F) , characterized and doped into the magnetic silica nanoparticles (Fe3O4@SiO2-F). Herein we [...]
Environmental Health Science and SBIR/STTR Small Business Grants
The NIEHS sets aside a percentage of extramural funds to support technology development for environmental health research through Small Business Innovation Research (SBIR) and Small Business Technology Transfer (STTR) grants. SBIR/STTR technologies supported by NIEHS [...]
Cyanide Detection by Highly Modified Sol-Gel Biocomposite Sensor
Cyanide is an important industrial chemical but is also very toxic. Cyanide binds strongly with hemoglobin than that of oxygen which causes histoxic hypoxia, if cyanide is ingested into the bloodstream. This pairing reaction can [...]
The influence of electrode on sensitivity of pH sensors fabricated on AlGaN/GaN heterostructures
In this work, we evaluated relationship between specific contact resistance and sensitivity of pH sensor by changing the ohmic contact metallization consisted of source and drain. The sample was fabricated for analysis of electrical characteristics [...]
Beyond Biomarkers: Array-Based Profiling for Diagnostics and High-Throughput Screening
The "chemical nose/tongue" approach presents a potential alternative to specific recognition and separations techniques. In this approach a sensor array is generated to provide differential interaction with analytes via selective receptors, generating a stimulus response [...]
Enhanced Kinetics of Enzymatic Nanosensors
Nanosensors employing quantum dots (QDs) and functional moieties such as enzymes are promising for diagnostics and chemical/biological threat activity. Their small size permits cell penetration and their inherent photochemical properties are well-suited for rapid, optical [...]
Multilayer optical strip for illumination, imaging and analysis
Gomez-Gonzalez E., Marquez-Rivas J., Perales-Esteve M.A., Mayorga-Buiza M.J., University of Seville, ES
An optical device (multilayer optical strip, MOS) is presented. It is composed of a small-sized, strip-shaped, multilayer, planar structure connected to a control unit. Active and passive optical elements allow for controlling the properties, spatial [...]
A Nanobiomimetic Neuronal Memcapacitor Serves as a Voltage Sensor and an Amperometry Sensor for Reagent-less Direct Detection of Sub pM Soluble Amyloid-beta
Amyloid-beta (A) plaque accumulation in the brain has been recognized to be associated with Alzheimer’s and dementia. Challenges of quantitation of Ab are the instability of soluble Ab1-42 and the protein interference plus the time [...]
In Situ Health Monitoring of Piezoelectric Sensors
The technology developed is an in-situ measurement system for monitoring the performance of piezoelectronic sensors, particularly accelerometers. With this technology, characteristics such as resonant frequency, response, cable status, connectivity, bonding and linear range, can be [...]
High-sensitive, direct and label-free detection technique of nanotoxic material using QCM
For the several decades, various nanomaterials are broadly used in industrial fields, research areas and commercialized products. Among many nanomaterials, silver ion, carbon nanotube, ZnO, and mercury ion etc are of the widely used nanomaterial [...]
Substrate addition and matrix optimization increased sensitivity and selectivity of the PLGA sensor, resulting in a stronger detection signal toward bacterial contaminations
Ibrisimovic M., Ibrisimovic N., Ibrisimovic M., Ibrisimovic N., Kesic A., Mehmedinovic M., Ibrisimovic M., Ibrisimovic N., Faculty of Science, University of Tuzla, BA
The aim of this work was to contribute to the development of a simple and cheap biomimetic sensor, providing a higher sensitivity and selectivity toward microbiological contaminations. An optimization of the matrix of the optical [...]
Nephrotoxicity of Dextran Functionalized Graphene Nanoparticles and Their Potential as Magnetic Imaging Contrast Agents for Renal Abnormalities
Lee S., Kanakia S., Toussaint J., Kukarni P., Chowdhury S.M., Khan S., Shroyer K., Moore W., Sitharaman B., Stony Brook University, US
Contrast-enhanced magnetic resonance angiography (MRA) employs the use of blood pool contrast agents (CA) such as gadolinium (Gd3+) complexes that allow for delayed phase arterial and venous imaging and improve the sensitivity in detecting small [...]
Journal: TechConnect Briefs
Volume: 3, Biotech, Biomaterials and Biomedical: TechConnect Briefs 2015
Published: June 14, 2015
Industry sectors: Medical & Biotech | Sensors, MEMS, Electronics
Topic: Sensors - Chemical, Physical & Bio
ISBN: 978-1-4987-4729-5