Papers – Page 2 – TechConnect Briefs

Microfluidics for multiplexing of core needle biopsies

Mojica W.D., Oh K.W., Lee H., Xue X., Furlani E.P., University at Buffalo, US

Image guided biopsies for the procurement of diagnostic tissue has proven to be safe, cost effective and useful. However, the amount of tissue obtained is often diminutive and may be exhausted for conventional diagnostic purposes. [...]

On the dynamic contact angle in spontaneous capillary flow

Berthier J., Gosselin D., Delapierre G., CEA-LETI, FR

Capillary actuation of fluids is an interesting solution when the gravitational forces are small: this is the case in space , or in microfluidic systems where gravity is negligible. The onset of spontaneous capillary flow [...]

Design, development and testing of apparatus to study gas diffusion in nanochannels

Karakitsiou S., Eder S.D., Holst B., Hoffmann A.C., University of Bergen, NO

In this work an apparatus, designed to measure gas diffusion through nanochannels, is introduced. All calculations for the construction have been made for 2000 nanochannels with a diameter of 100 nm and a length of [...]

The Development of an Automated Nano Sampling Handling System for Nanometre Protein Crystallography Experiments

Docker P., Axford D., Prince M., Cordovez B., Kay J., Stuart D., Evans G., Diamond light Source, UK

As the world’s synchrotrons and X-FELs endeavour to meet the need to analyse ever-smaller protein crystals, there grows a requirement for a new technique to present nano-dimensional samples to the beam for X-ray diffraction experiments.The [...]

Negative Dielectrophoretic Force based High Efficiency and High Throughput Cell Sorting System Harnessing Paired Electrode Arrays and a Meso Size Channel

Lee D., Hwang B., Kim B., Korea Aerospace University, KR

Dielectrophoresis activated cell sorters (DACS), which exploit intrinsic dielectric properties of target cells, are highlighted as an alternative cell sorting method. Nonetheless, the DACS performing in micro channel have limitation with throughput while they accomplished [...]

A Simple Method for Fabrication of Microarrays and Microfluidic Device Using PDMS Stamp

Lee H., Koh D., Oh K.W., SUNY at Buffalo, US

We describe a simple micro-fabrication method by using polydimethylsiloxane (PDMS) stamp on a glass substrate. While the microwells used previously facilitated the cell-to-cell formation by PDMS stamping method, not only should it be carefully controlled [...]

The application of 3D printing to study microfluidic architecture for ‘on chip’ mixing systems for SRCD and UV spectroscopy

Prince M., Docker P., Burton C., Hussain R., Kay J., Silgardi G., Diamond light Source, UK

Circular dichroism (CD) is the differential absorption of left- and right-handed circularly polarized light. It is a form of spectroscopy used to determine the optical isomerism and secondary structure of molecules, and to study a [...]

The Automation of Protein Crystal Presentation for X Ray Diffraction Experiments using Standing Acoustic Waves in a Microfluidic Chip Environment

Burton C., Docker P., Prince M., Leaper M., Kay J., Stuart D., Evans G., Diamond light Source, UK

As the pressure continues to grow on Diamond and the world’s synchrotrons for higher throughput of diffraction experiments, new and novel techniques are required for presenting these micron dimension crystals to the X ray beam. [...]

Recent advances in capillary microflows for point-of-care and home-care devices

Berthier J., Gosselin D., Huet M., Cubizolles M., Delapierre G., CEA/LETI/MINATEC, FR

Biotechnology has been recently seeing fundamental evolutions: first, a clear shift towards biological applications; second a trend towards the design and fabrication of portable devices; third the choice of inexpensive materials such as plastic or [...]

Wireless, One-way, Sensor to Base Station Monitoring System for Explosive and Non-hazardous Environments

Jensen S.L., NASA - Stennis Space Center, US

The technology developed is a monitoring system that includes a base station and at least one sensor unit mounted at some distance away, which is in wireless, one-way communication with the base station. The sensor [...]