Concern-Driven Approach to human health risk assessment of nanomaterials: A Nanoparticle Screening Assessment Framework

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The framework proposed here was developed under the Canada-US Regulatory Cooperation Council (RCC) Nanotechnology Initiative and represents a concern-driven approach to focus human health concerns and additional testing requirements for nanoparticles based on their physical [...]

Dose- and Time-dependent Effects of Sub-chronic Functionalized MWCNT Exposure on Human Mesothelial Cell Neoplastic Transformation Potential

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Multi-walled carbon nanotubes (MWCNTs) are characterized by asbestos-like fiber morphology and surface chemistries. Physicochemical properties of MWCNTs that influence pleural mesothelioma potential are unknown, but critically needed to enhance safe-by-design nanotechnology. We hypothesized that surface [...]