Topic: Personal & Home Care, Food & Agriculture
Characterisation of Drug Nanoparticles by Atomic Force Microscopy
A key consideration when developing a drug nanoparticle formulation, particularly when intended for parenteral administration, is the control of particle size, shape and physical properties such as dissolution rate and stability with respect to Ostwald [...]
Thermodynamic Characterization of Nanoscale Materials
“The largest barrier to rational design and controlled synthesis of nanomaterials with predefined properties is the lack of fundamental understanding of thermodynamic and kinetic processes at the nanoscale. …Bulk material properties are not size-dependent, but [...]
Transmission Spectrum of PDMS in 4-7µm Mid-IR Range for Characterization of Protein Structure
Infrared (IR) spectroscopy has been an important tool to characterize secondary structure of proteins for decades. To extend PDMS-based micro-device into spectroscopic characterization of proteins for structural study, the transmission spectrum of PDMS over the [...]
Analysis of Surface Interaction between TiO2 Fine Particles with Different Surface Modification in Isoparaffin by Using Colloid Probe AFM
Kamiya H., Suzuki M., Kikuchi M., Iijima M., Tsukada M., Tokyo University of Agriculture and Technology, JP
To control the dispersion stability of nanometer scaled fine inorganic particles in organic solvent, various kinds of surface modification on particles have been carried out. This paper focused on the surface modification on titanium oxide [...]
Multiscale Modeling of Polymer Based Nanomaterials
In materials design and engineering there is a need for fundamental information that spans large scales of time and distances, from the quantum chemical nature of interactions to the macroscopic mechanical, and electrical properties. In [...]
Lattice Boltzmann simulation of emulsification in microfluidics devices
van der Graaf S., van der Sman R.G.M., van der Graaf S., van der Sman R.G.M., Wageningen University, NL
Using microdevices we investigate the manufacturing of surfactant stabilised monodisperse food emulsions. Design of the process is a complicated matter, involving knowledge of wetting behaviour, droplet breakup in confined systems, surfactant dynamics coupled to droplet [...]
Interaction between polyether- poly (2-dimethylaminoethyl methacrylate)copolymers and phospholipid model vesicles – implications for gene delivery efficiency
Our previous studies have demonstrated that surface-active copolymers of Pluronic® surfactants and tertiary amino polycations such as poly (2-dimethylaminoethyl methacrylate) (pDMA) possess an enhanced DNA transfection efficiency compared to pDMA homopolymers. The transfection efficiencies of [...]
Spontaneously Forming Unilamellar Nano-Sized Vesicles – Polydispersity, Size, Shape and Stability
Nieh M-P, Raghunathan V.A., Huang C-Y, Pencer J., Harroun T., Katsaras J., National Research Council at Canada, CA
Unilamellar vesicles (ULV) made up entirely of biologically relevant materials can serve as carriers for drug delivery or gene therapy. Compared to extrusion and sonication methods, traditionally used for producing ULV, spontaneously forming ULV offer [...]