UCSD – TechConnect Briefs

Multiplexed protein detection using antibody-conjugated microbead arrays assembled on a microfabricated electrophoretic device

Barbee K.D., Hsiao A.P., Roller E.E., Huang X., UCSD, US

We report the development of a microfabricated electrophoretic device for assembling high-density arrays of antibody-conjugated microbeads for chip-based protein detection. The device consists of a flow cell formed between a gold-coated silicon chip with an [...]

Analytic Charge Model for Double-Gate and Surrounding-Gate MOSFETs

Yu B., Lu H., Lu W-Y, Lu H., Lu W-Y, Taur Y., UCSD, US

An analytic charge model for both double-gate (DG) and surrounding-gate (SG) MOSFETs is presented. With only the mobile charge term, Poisson’s equation is rigorous solved and the analytic electrostatic potential is derived. The development of [...]

Functionalized Quantum Dot Characterization and Applications in Neurosciences

Pathak S., Davidson M., Sharp C., Silva G., UCSD, US

Quantum dot nanocrystals are nanometer sized semiconductor particles, which can be used for labeling biological systems. A critical issue that has not been addressed is determining the number of antibodies bound to nanoparticles. We have [...]

Charge-storage calculation for Si-based bipolar transistors from device simulation

Tran H., UCSD, US

Various methods for calculating regional charge storage components in bipolar transistors fromdevice simulation results are compared with respect to their usefulness for compact modeling. Themethods are evaluated for Si and SiGe transistors with very different [...]

Quantum Dot Nanocrystals in Neurosciences

Pathak S., Cao E., Davidson M., Jin S., Silva G., UCSD, US

We have developed labeling methods using commercially available quantum dots specific to neurons and glia (Pathak S, in press) and have used these tools to label GFAP intermediate filament cellular bridges as well as integrin [...]