Development of Nanoparticle-Based Gold Contrast Agent for Photoacoustic Tomography

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Photoacoustic tomography (PAT) utilizes non-ionizing energy to obtain structural/functional information with high spatial resolution and sensitivity. Heterogeneous absorption of optical energy in biological tissues results in differentially expressed acoustic signals yielding spatial/temporal information. A critically [...]

Rhodamine B Isothiocyanate-Modified Ag Nanoaggregates on Dielectric Beads: A Novel Surface-Enhanced-Raman-Scattering and Fluorescent Imaging Material

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Ag-deposited silica and polystyrene beads are efficient surface-enhanced-Raman-scattering (SERS) substrates that can be used as core materials of SERS-based biosensors. In this work, we report that once rhodamine B isothiocyanate (RhBITC) is adsorbed onto them, [...]