Micro & Bio Fluidics, Lab-on-Chip – Page 7

An Integrated Biometric Platform for Evaluation of Targeted Drug Delivery

Liu Y., Thomas A., Uhl C., Wang S., He R., Lehigh University, US

In order to develop in vitro methods, which more closely resemble in vivo environments, a novel technology involving the use of microfluidic devices, which more closely mimic blood vessels has been developed. The technology has [...]

Low-cost spin-coatable, Transferable, and High-k Ion Gel Dielectric for Flexible Eletrowetting

Narasimhan V., Sanjairaj V., Park S.Y., National University of Singapore, SG

Electrowetting-on-dielectric (EWOD) is an emerging liquid-handling technology, enabling the wettability modulation of a liquid on a solid surface with an applied electric field. Recently, EWOD has been attractively used on flexible substrates to show potential [...]

Bottom-up Nanofabrication of Crystalline Structures of Magnetic Nanoparticles

Xue X., Furlani E.P., SUNY at Buffalo, US

A bottom-up approach to the nanofabrication of three-dimensional (3D) crystalline structures of magnetic core-shell nanoparticles is presented. The approach is based on self-assembly and involves the use of soft-magnetic template elements to guide the assembly [...]

Microfluidics for multiplexing of core needle biopsies

Mojica W.D., Oh K.W., Lee H., Xue X., Furlani E.P., University at Buffalo, US

Image guided biopsies for the procurement of diagnostic tissue has proven to be safe, cost effective and useful. However, the amount of tissue obtained is often diminutive and may be exhausted for conventional diagnostic purposes. [...]

On the dynamic contact angle in spontaneous capillary flow

Berthier J., Gosselin D., Delapierre G., CEA-LETI, FR

Capillary actuation of fluids is an interesting solution when the gravitational forces are small: this is the case in space , or in microfluidic systems where gravity is negligible. The onset of spontaneous capillary flow [...]

Design, development and testing of apparatus to study gas diffusion in nanochannels

Karakitsiou S., Eder S.D., Holst B., Hoffmann A.C., University of Bergen, NO

In this work an apparatus, designed to measure gas diffusion through nanochannels, is introduced. All calculations for the construction have been made for 2000 nanochannels with a diameter of 100 nm and a length of [...]

The Development of an Automated Nano Sampling Handling System for Nanometre Protein Crystallography Experiments

Docker P., Axford D., Prince M., Cordovez B., Kay J., Stuart D., Evans G., Diamond light Source, UK

As the world’s synchrotrons and X-FELs endeavour to meet the need to analyse ever-smaller protein crystals, there grows a requirement for a new technique to present nano-dimensional samples to the beam for X-ray diffraction experiments.The [...]

Negative Dielectrophoretic Force based High Efficiency and High Throughput Cell Sorting System Harnessing Paired Electrode Arrays and a Meso Size Channel

Lee D., Hwang B., Kim B., Korea Aerospace University, KR

Dielectrophoresis activated cell sorters (DACS), which exploit intrinsic dielectric properties of target cells, are highlighted as an alternative cell sorting method. Nonetheless, the DACS performing in micro channel have limitation with throughput while they accomplished [...]

A Simple Method for Fabrication of Microarrays and Microfluidic Device Using PDMS Stamp

Lee H., Koh D., Oh K.W., SUNY at Buffalo, US

We describe a simple micro-fabrication method by using polydimethylsiloxane (PDMS) stamp on a glass substrate. While the microwells used previously facilitated the cell-to-cell formation by PDMS stamping method, not only should it be carefully controlled [...]

The application of 3D printing to study microfluidic architecture for ‘on chip’ mixing systems for SRCD and UV spectroscopy

Prince M., Docker P., Burton C., Hussain R., Kay J., Silgardi G., Diamond light Source, UK

Circular dichroism (CD) is the differential absorption of left- and right-handed circularly polarized light. It is a form of spectroscopy used to determine the optical isomerism and secondary structure of molecules, and to study a [...]