Micro & Bio Fluidics, Lab-on-Chip – Page 6

Design, development and testing of apparatus to study gas diffusion in nanochannels

Karakitsiou S., Eder S.D., Holst B., Hoffmann A.C., University of Bergen, NO

In this work an apparatus, designed to measure gas diffusion through nanochannels, is introduced. All calculations for the construction have been made for 2000 nanochannels with a diameter of 100 nm and a length of [...]

The Development of an Automated Nano Sampling Handling System for Nanometre Protein Crystallography Experiments

Docker P., Axford D., Prince M., Cordovez B., Kay J., Stuart D., Evans G., Diamond light Source, UK

As the world’s synchrotrons and X-FELs endeavour to meet the need to analyse ever-smaller protein crystals, there grows a requirement for a new technique to present nano-dimensional samples to the beam for X-ray diffraction experiments.The [...]

Negative Dielectrophoretic Force based High Efficiency and High Throughput Cell Sorting System Harnessing Paired Electrode Arrays and a Meso Size Channel

Lee D., Hwang B., Kim B., Korea Aerospace University, KR

Dielectrophoresis activated cell sorters (DACS), which exploit intrinsic dielectric properties of target cells, are highlighted as an alternative cell sorting method. Nonetheless, the DACS performing in micro channel have limitation with throughput while they accomplished [...]

A Simple Method for Fabrication of Microarrays and Microfluidic Device Using PDMS Stamp

Lee H., Koh D., Oh K.W., SUNY at Buffalo, US

We describe a simple micro-fabrication method by using polydimethylsiloxane (PDMS) stamp on a glass substrate. While the microwells used previously facilitated the cell-to-cell formation by PDMS stamping method, not only should it be carefully controlled [...]

The application of 3D printing to study microfluidic architecture for ‘on chip’ mixing systems for SRCD and UV spectroscopy

Prince M., Docker P., Burton C., Hussain R., Kay J., Silgardi G., Diamond light Source, UK

Circular dichroism (CD) is the differential absorption of left- and right-handed circularly polarized light. It is a form of spectroscopy used to determine the optical isomerism and secondary structure of molecules, and to study a [...]

The Automation of Protein Crystal Presentation for X Ray Diffraction Experiments using Standing Acoustic Waves in a Microfluidic Chip Environment

Burton C., Docker P., Prince M., Leaper M., Kay J., Stuart D., Evans G., Diamond light Source, UK

As the pressure continues to grow on Diamond and the world’s synchrotrons for higher throughput of diffraction experiments, new and novel techniques are required for presenting these micron dimension crystals to the X ray beam. [...]

Recent advances in capillary microflows for point-of-care and home-care devices

Berthier J., Gosselin D., Huet M., Cubizolles M., Delapierre G., CEA/LETI/MINATEC, FR

Biotechnology has been recently seeing fundamental evolutions: first, a clear shift towards biological applications; second a trend towards the design and fabrication of portable devices; third the choice of inexpensive materials such as plastic or [...]

Micro, Nano & Bio Fluidics

Plasmonic Nanocages as Photothermal Transducers for Laser Induced Heating and Bubble Generation

Karampelas I.H., Alali F., Furlani E.P., SUNY-Buffalo, US

A series of new computational models is introduced to demonstrate several photonic and thermo-fluidic details of the photothermal process associated with nanosecond-pulsed, laser-heated gold nanocages. Such models can be used to simulate energy conversion within [...]

Guidelines for choosing an appropriate turbulence model when simulating blood flows in cardiovascular devices

Simpson B.A.F., Tansley G.D., Griffith University, AU

A systematic and detailed comparative study of computational results with validating experimental data has helped define the turbulence models that are most appropriate for predicting the velocity fields and shear forces in blood flows. The [...]