Micro & Bio Fluidics, Lab-on-Chip – Page 33

Coin-Shaped Reactor in Microfluidic Devices Used for Radiopharmaceutical Synthesis

Elizarov A.M., Kolb H.C., van Dam R.M., Heath J.R., Padgett H.C., Huang J., Daridon A., California Institute of Technology, US

A microfluidic device designed and optimized for the multi-step synthesis of PET (Positron Emisssion Tomography) probes is presented. It is the first device in its class to produce radiopharmaceuticals of sufficient quality and quantity (over [...]

Integrated microfluidic device to monitor the cells acidification rate in nanoliter volumes using microfabricated iridium oxide electrodes

Ges I.A., Ivanov B.L., Baudenbacher F.J., Vanderbilt University, US

In our work we describe a new approach to measure pH differences in microfluidic devices and demonstrated acidification rate measurements in on-chip cell culture systems with nanoliter wells. We used two miniaturized identical iridium oxide [...]

Thermally Induced Marangoni Instability of Liquid Microjets with Application to Continuous Inkjet Printing

Furlani E.P., Price B.G., Hawkins G., Lopez A.G., Eastman Kodak Co., US

Liquid microjets are inherently unstable and can be broken into droplets in a controllable fashion via thermal modulation of surface tension. Such modulation can be achieved using CMOS/MEMS technology by integrating resistive heating elements around [...]

Analysis of the Droplet Ejection for Piezoelectric-driven Industrial Inkjet Head

Sim S., Park C., Park S-J, Park C., Park S-J, Yoo Y., Kim Y., Joung J., Oh Y., Samsung Electro Mechanics Co., KR

A hybrid design tool combining one-dimensional(1D) lumped parameter model and three-dimensional(3D) computational fluid dynamics (CFD) approach has been developed and applied to industrial inkjet head design for the application of direct writing on printed circuit [...]

Magnetohydrodynamic (MHD) Complex Flow Generation in Microchannel

Kim D.S., Kwon T.H., Pohang University of Science and Technology (POSTECH), KR

In this paper, we present design methodologies for magnetohydrodynamic (MHD) complex flow generation in a simple straight microchannel in which electrodes are patterned on two side walls and bottom wall. The required applied voltage conditions [...]

Capillary filling speed in silicon dioxide nano-channels

Jarlgaard S.E., Mikkelsen M.B.L., Skafte-Pedersen P., Bruus H., Kristensen A., Technical University of Denmark, DK

We present a simple silicon-based fabrication technique for nanocapillaries based on controlled growth of silicon-dioxide, UV lithography, etching with etch-stop, and glass wafer bonding. Our approach improves state-of-the-art with respect to the obtained cross-wafer homogeneity [...]

Macromodeling for Microfluidic Channels

Kuo C-W, Chein C-M, Yang Y-J, National Taiwan University, TW

In this paper, we present a methodology of generating microfluidic macromodels (reduced-order models) for 3-D non-linear microchannels. Compared with the full-meshed simulations, the generated macromodels not only provide accuracy results, but also give three-orders-of-magnitude speed-ups. [...]

Electric Field Driven Motion of Flexible Polyelectrolytes – A Molecular Dynamics Study

Lo T.S., Khusid B., Acrivos A., Koplik J., New Jersey Institute of Technology, US

Our work aims to develop multi-scale computational procedures for simulating the dielectrophoretic behavior of biomolecules in micro- and nano-electrofluidics, which combine electrohydrodynamics with molecular theories for the macromolecule polarization caused by the distortion of the [...]

Infinitely fast reactions in micromixers

Gleeson J.P., University College Cork, Ireland, IE

Efficient mixing to promote chemical reactions is extremely desirable in lab-on-a-chip microfluidic devices, but is difficult to achieve in the typical low Reynolds-number flows. Numerical simulation of the high Peclet-number case common in microfluidics is [...]

Simulation of Electrokinetic Flow and Analyte Transport in Nano Channels

Feng J.J., Krishnamoorthy S., Wang G.W., Sundaram S., CFD Research Corporation, US

This paper demonstrates the electrokinetic flow and transport of charged and neutral analytes in nanochannels by solving full system of governing Poisson-Nernst-Planck equations without any assumptions. The issues related to the spatial and time scales [...]