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HomeTopicsMicro & Bio Fluidics, Lab-on-Chip

Topic: Micro & Bio Fluidics, Lab-on-Chip

Novel Parameters for Rapid Blood Separation on a Centrifugal Platform

Gorkin R., Kim T-H., Madou M., Cho Y-K, University of California Irvine, US
Centrifugal microfluidic platforms are emerging as strong candidates for advanced integrated clinical diagnostics for such applications as automated immunoassay processing and nucleic acid analysis, however several implementation challenges limit their widespread use today. Purification of [...]

Biomolecular Adsorption Phenomena in Electrowetting-Based Digital Microfluidic Devices

Ahmadi A., Devlin K.D., Najjaran H., Holzman J.F., Hoorfar M., University of British Columbia, CA
Digital microfluidic lab-on-a-chip technology has been a new trend in miniaturizing biomedical platforms. However, nonspecific adsorption of these biomolecules has proven to be one the greatest sources of uncertainties for these biofluidic chips. Unwanted adsorption [...]

Design of a normally closed piezoelectric micro valve

Zähringer S., Menacher M., Kirchner P., Schwesinger N., Technische Universitaet Muenchen, DE
In a previously published paper a piezoelectric actuator using surface electrodes was investigated in a macro-microscopic approach. Bases on those results a normally closed piezoelectric micro valve was devoloped. Therefore the electrode structures were minimized [...]

Transitions Between Epithelial and Mesenchymal States in Microfluidic Platform: Acquisition of Malignant and Stem Cell Traits

Aref A.R., Huang R.Y.J., Kang W., Jing S.W., Thiery J.-P., Kamm R.D., SMART, SG
Epithelial–mesenchymal transition (EMT) is an indispensable mechanism during morphogenesis, as without mesenchymal cells, tissues and organs will never be formed. Transitions between epithelial and mesenchymal states have crucial roles in embryonic development and without EMT, [...]

Vapor-assisted bonding of poly(dimethylsiloxane) and silicon-based substrates

Sofla A.Y.N., Martin C., University of Toronto, CA
We present a novel method to reliably bond PDMS to glass, Si, SiO2 and PDMS. In this vapor-assisted method the surface of the PDMS is first brought into contact with the substrate. The PDMS-substrate structure [...]

Continuous Separation of Non-Magnetic Particles through Negative Magnetophoresis inside Ferrofluids

Zhu T., Marrero F., Mao L., The University of Georgia, US
We present a simple, effective and label-free continuous flow non-magnetic microparticle separation scheme in a microfluidic device under static magnetic fields. The separation process is based on negative magnetophoresis and uses water-based ferrofluids. We exploit [...]

Experimental Study of Drying/Evaporation in an Effective 2D Porous Medium

Yiotis A.G., Tsimpanogiannis I.N., Stubos A.K., National Center for Scientific Research “Demokritos”, GR
Liquid-to-gas phase change, where the mass transfer that drives the process occurs in the gas phase, and the subsequent growth of the produced gas phase within a porous medium, is involved in a wide variety [...]

Slip boundary conditions in nanofluidics from the molecular theory of solvation

Kobryn A.E., Kovalenko A., National Institute for Nanotechnology, CA
We propose the first-ever derivation and calculation of the hydrodynamic slip length from the first principles of statistical mechanics, based on a combination of linear response theory and equilibrium molecular theory of solvation. The slip [...]

Micro & Nano Fluidics

Effects of Memories of Polarization Interactions during Particle Transport Induced by One Gradient AC Electric Field

Shen Y., Tada S., Qiu Z., The City College of the City University of New York and New York Center for Biomedical Engineering, US
On the Nanotech 2008 in Boston, we reported our experimental observations of the particle instability and island-like structures in the suspension of poly alpha olefin particles and corn oil when the suspension was exposed to [...]

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