Materials Characterization & Imaging – Page 57

Quantum Dots for Multimodal Bioimaging and Sensing Applications

Santra S., Yang H., Sabui S.K., Sharma P., Holloway P.H., Walter G.A., Moudgil B.M., Scott E., University of Central Florida, US

Fluorescent quantum dots (Qdots) have demonstrated their potential in diagnostic bioimaging applications in vitro. For in vivo bioimaging applications, however, the embodiment of additional properties such as paramagnetism onto the same fluorescent probes is highly [...]

Functionalized Quantum Dot Characterization and Applications in Neurosciences

Pathak S., Davidson M., Sharp C., Silva G., UCSD, US

Quantum dot nanocrystals are nanometer sized semiconductor particles, which can be used for labeling biological systems. A critical issue that has not been addressed is determining the number of antibodies bound to nanoparticles. We have [...]

Application of Quantum dots for the lifespan study of Caenorhabditis elegans

Huang G.S., Chang K-M, Chen Y-C, Yeh L-G, National Chiao Tung University, TW

The progress in identifying drugs that extend lifespan of Caenorhabditis elegans has been slow partly due to the tedious and labor-intensive nature of drug screening. We labeled C. elegans by mixing quantum dots, FITC, or [...]

In vivo imaging by luminescent carbon nanotubes

Shi D., Guo Y., Dong Z., Lian J., Wang W., Liu G., Ewing R., University of Cincinnati, US

There is currently an increasing need for early detection of cancer before anatomic anomalies are visible. A major challenge in cancer diagnosis is to be able to locally biomark the cancer cells in clinical pathology [...]

Synthesis, Encapsulation and Functionization of Composite Organic-Inorganic Nanoparticles with Distinctive Surface Enhanced Raman Signatures

Zhang J., Lu Y., Lutz B., Cao M., Qin H., Yamakawa M., Dentinger C., Nguyen L., Chmura A.J., Zhu J., Lutz B., Sung K-B, Swartz K., Wang L., Su X., Sun L., Sung K-B, Berlin A.A., Chan S., Sun L., Sung K-B, Intel Corporation, US

Composite organic-inorganic nanoparticle (COIN) is a new type of optical label for multiplex biomolecule detection. It has strong Raman signal intensity and potentials for a large number of unique Raman signatures. We have developed methods [...]

In Situ Investigation of Uptake Phenomena of Biological Molecules and Silica Nanoparticles into Mammalian Cells in Microstructures

Lee W.G., Bang H., Yun H., Kim J.A., Cho K., Shin Y.S., Chung C., Chung N.C., Chung C., Chung N.C., Chang J.K., Han D-C, Seoul National University, KR

Electroporation is a powerful gene transfection method to deliver foreign biological molecules such as DNA and protein into living cells with electric pulsations. However, conventional cuvette-type electroporation techniques generally suffer from poor transfection efficiency and [...]

Fluorescent Structural DNA Nanoparticles Functionalized With Phosphate-Linked Nucleotide Triphosphates

Williams J.G., Reynolds B.L., Keefe K., Anderson J.P., LI-COR Biosciences, US

Structural DNA nanoparticles functionalized with phosphate-linked nucleotide triphosphates (dNTPs) were tested as a source of dNTPs for DNA polymerase. The particles were prepared by strand-displacement polymerization from a self-complementary circular template. An intercalating dye (SYBR-101) [...]

Biomarkers & Nanoparticles

Morphology effect dependent on the synthesis method of KxIr1-xO2 system

Ramírez E., Chavira E., Baños L., Soto Guzmán A.B., Guzmán J., Flores C., Universidad Nacional Autonoma de Mexico, MX

We focus our attention on the synthesis of the solid solution of KxIr1-xO2 with x = 0.25. This solid solution was obtained by the solid-state reaction and sol-gel method using IrO2 and K2CO3 as starting [...]

A Novel Ultrasonic Method for Characterizing Suspensions of Nanoparticles

Africk S., Colton C.K., Prodyne Corp. and Massachusetts Institute of Technology, US

Originally developed to measure concentration of human Islets of Langerhans in transplant preparations, the Ultrasonic Pulsed Doppler (USPD) method uses a single transducer as both source and receiver of pulsed ultrasound to measure backscattered energy [...]