In Situ Investigation of Uptake Phenomena of Biological Molecules and Silica Nanoparticles into Mammalian Cells in Microstructures

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Electroporation is a powerful gene transfection method to deliver foreign biological molecules such as DNA and protein into living cells with electric pulsations. However, conventional cuvette-type electroporation techniques generally suffer from poor transfection efficiency and [...]

Microfabricated Fluorescence-Activated Cell Sorter with Hydrodynamic Flow Manipulation

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Presented is a novel flow manipulation and particle detection method for the microfabricated fluorescence-activated cell sorter (FACS). With hydrodynamic flow manipulation which includes passive flow channeling and hydrodynamic actuation with nozzle flow, we have developed [...]