Diagnostics & Bioimaging

Multiplex Express In Vitro Diagnostics based on Magnetic Nanoparticles

Nikitin M.P., Nikitin P.I., Guteneva N.V., Bragina V.A., Znoyko S.L., Orlov A.V., Gorshkov B.G., Nikitin M.P., Nikitin P.I., General Physics Institute, Russian Academy of Sciences, RU

Magnetic nanoparticles (MP) have provided many breakthrough solutions for life science. The immense potential of MP as labels in advanced immunoassays stems from the fact that they, unlike optical labels, can be easily detected inside [...]

Novel fluorescent nanoparticles for ultrasensitive identification of nucleic acids by optical methods

Westergaard Mulberg M., Taskova M., Okholm A., Kjems J., Astakhova K., University of Southern Denmark, DK

There have been an enormous interest in new amplification-free detection methods. A tremendous progress has been made in fluorescence based optical detection of biomolecules, which here resulted in the synthesis of novel ultra bright fluorescent [...]

Carcinoma cellular uptake, imaging, and targeting by RGDS- and TAT-conjugated upconversion and/or magnetic nanoparticles

Horák D., Kostiv U., Proks V., Jirák D., Institute of Macromolecular Chemistry AS CR, CZ

Specific targeting and in vivo visualization of cancer cells is of crucial importance for early detection and treatment of cancer. We have developed monodisperse poly(ethylene glycol) (PEG)-modified SiO2-coated Fe3O4 superparamagnetic nanoparticles [1] with size tuned [...]

Point-of-Care (POC) Micro Biochip for Cancer Diagnostics

Nunna B.B., Lee E-S, New Jersey Institute of Technology, US

American cancer society stated that a total of 1,685,210 new cancer diagnosed cases out of which 595,690 deaths from cancer are expected to be reported in the United States of America in 2016. Unfortunately Cancer [...]

Amplification-free liquid biopsy by fluorescence approach

Uhd J., Taskova M., Okholm A., Astakhova K., University of Southern Denmark, DK

Diagnostics of cancer associated ctDNA, BRAF V600E, KRAS G12D and KRAS G13D respectively. By the use of modern fluorescence microscopy and fluorescently labeled mutation specific LNA/DNA probes. Which resulted in a mutation specific detection.

Diagnostics & Bioimaging

A CMOS Lab-On-A-Chip For Neuron Monitoring And Stimulation

Ghallab Y.H., Ismail Y., Center of Nano Electronics and Devices (CND) at American University in Cairo/ Zewail City of Science and Technology, Cairo, Egypt, EG

Many tools have been established to monitor neural activity such as patch pipettes and microelectrodes, which are electrolyte filled glass tubes used to create intracellular contacts by rupturing the cell membrane and directly measuring the [...]

Electrochemical Detection of Alcohol using Enzyme Sensor with Chromatography Paper and its Potential Application as halal Sensor

Musa M.S., Kuretake T., Harada Y., Hori F., Uno S., Ritsumeikan University, JP

The Islamic law forbids Muslims from consuming food that contains porcine derivatives and alcohol, among others. The halal term is not limited to only the food ingredients but also considers the absence of non-halal species [...]

Novel silicon microdosimeter based on 3D cylindrical structures

Guardiola C., Carabe-Fernández A., Gomez F., Pellegrini G., Fleta C., Quirion D., Lozano M., University of Pennsylvania, US

A new design of a solid-state-detector based on silicon microfabrication is provided in this work in order to create a novel microdosimeter. This microdosimeter improves the performance of existing microdosimeters using three-dimensional microfabrication technology development. [...]