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HomeTopicsDiagnostics & Bioimaging

Topic: Diagnostics & Bioimaging

Ligand-dependent changes in the SPR of magnetic nanoparticles

Radu L., Caruntu D., White M., Wiley J., Hanson P., University of New Orleans, US
Currently, there is an increasing interest in using magnetite nanoparticles in biological and medical applications. The interest is driven by a combination of their biocompatibility, chemical stability and magnetic properties. Magnetite nanoparticles with diameter 10 [...]

Fast and Easy Detection System of Protein Glycosylation by Using Resonant Energy Transfer between Nanoparticles

Oh E., Lee D., Kim H-S, Korea Advanced Institute of Science and Technology, KR
We construct the new glycosylation detection system using Resonance Energy Transfer (RET) between gold nanoparticles (AuNPs) and semiconductor quantum dots (QDs). RET can be induced by biomolecular interactions between concanavalin A (conA)-conjugated AuNP (conA-AuNP) as [...]

Applications of Dielectrophoretic / electrohydrodynamic electrodes for concentration of biological nanoparticles

Fatoyino H.O., Huebner Y., Hoettges K.F., Hughes M.P., Labeed F.H., University of Surrey, UK
Dielectrophoresis (DEP) is a phemomenon of induced particle motion in non-uniform electric fields. The effect is frequency dependent; by monitoring the motion of particles in AC fields and ananlysing the change in motion with frequency, [...]

Nanoengineered Encapsulation of Organic Microcrystal as Novel Biolabels

Mak W.C., Cheung K.Y., Renneberg R., Trau D., National University of Singapore, SG
Here we report on our latest developments for nanoengineered encapsulation and surface design of micro and submicron crystals for biochemcial assay. Improvement has been made by decreasing the size of the organic crystals to submicrometer [...]

Biomolecular diagnostics by a magnetic lab-on-a-chip

Brückl H., Eggeling M., Heer R., Nöhammer C., Schotter J., ARC Seibersdorf Research GmbH, AT
Compared to the established fluorescent labeling method, the use of magnetic markers in biochip sensors has important advantages with respect to the detection of biomolecules at low concentrations. Additionally, the direct availability of an electronic [...]

A Sensitive Peptide-Nanotube Based Pathogen Assay

MacCuspie R.I., Banerjee I.A., Gummalla S., Mostowski H., Krause P., Matsui H., Hunter College, US
A novel peptide nanotube-based multiplexed pathogen assay has been developed that has high sensitivity, detecting as few as 100 pathogens per mL in as little as 0.5mL. Multifunctional nanotubes detect viruses by selectively binding antibody [...]

Direct-Write CMOS-Based Laboratory-On-Chip

Ghafar-Zadeh E., Sawan M., Therriault D., École Polytechnique de Montréal, CA
Over the recent years, the identification of genes which influence many diseases has been highly demanded and now, molecular diagnosis is most promising technology to offer fast and early detection of diseases to a maximum [...]

Magnetic Devices for Ultra High Throughput Biological Analysis

Mitrelias T., Jiang Z., Llandro J., Bland J.A.C., University of Cambridge, UK
In this report we present an integrated microfluidic cell for detecting and sorting magnetic beads in solution. The cell has been developed for magnetic biosensing, which comprises both magnetoresistive sensors optimized for the detection of [...]

Biosensors Fabricated through Electrostatic Assembly of Enzymes/Polyelectrolyte Hybrid Layers on Carbon Nanotubes

Lin Y., Liu G., Wang J., Pacific Northwest National laboratory, US
Carbon nanotubes (CNTs) have emerged as a new class of nanomaterials that is receiving considerable interest because of their unique structure and mechanical and electronic properties. One promising application of CNTs involves their use in [...]

Carbon Microstructures for Glucose Biosensor

Xu H., Malladi K., Wang C., Madou M.J., University of California Irvine, US
In this work we report on a novel design and fabrication of glucose sensor based on carbon post electrode array. Apart from the fact that carbon has a wide electrochemical stability window, one advantage of [...]

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