Cancer Nanotechnology – Page 5

Iron-sequestering molecules play a pivotal role in the mechanism of toxicity of SWNTs on fungal and bacterial cells

Chaves J.S., Chaves S.J., Zuniga P., Chaves J.S., Chaves S.J., Instituto Tecnologico de Costa Rica, CR

In this study we described that iron-sequestering molecules are responsible for the toxicity of iron containing SWNTs to microorganisms. After incubating different concentrations of functionalized SWNTs with bacteria and fungal cells, it was found that [...]

Magnetic Targeting of Human Aortic Smooth Muscle Cells for Rapid Closure and Healing of Intracranial Aneurysm/Pseudoaneurysm

Arias S.L., Alucozai M., Pastrana F., Reece L.M., Kempaiaih R., Pavon J.J., Allain J.P., Purdue University, US

A novel approach is proposed in this study using a magnetic strategy to address the current disadvantages of detachable coils and stent grafts for aneurysm/pseudoaneurysm treatment. It consists of a patch facing the aneurysm neck [...]

Noble metal nanoparticles for plasmonic photothermal therapy of atherosclerosis

Kharlamov A., Gabinsky J., Erasmus University Medical Center, NL

Background: Our previous bench studies PLASMONICS and NANOM First-in-Man trial documented TAV reduction up to unprecedented 79.4 and 60.3 mm3 respectively with high level of safety and feasibility. Methods: The completed randomized two arm (1:1) [...]

Effects of ZnO nanoparticles and ZnCl2 solution on rat liver and kidney

Ben Rhouma K., Ben Slama I., Amara S., Rihane Ben Younes N., Mrad I., Omri K., El Ghoul J., El Mir L., El Ghoul J., El Mir L., Ben Rhouma K., Ben Slama I., Abdelmelek H., Sakly M., Faculty of Sciences, TN

Recent studies have shown that Zn2+ is released from the surface of ZnO NPs when they are suspended in an aqueous state.The aim of this study was to evaluate the effects of ZnO nanoparticles (ZnO-NPS) [...]

Reversing Coagulopathy and Internal Hemorrhage with Functionalized Nanoparticles

Kudela D., May-Masnou A., Smith S.A., Braun G., Pallaoro A., Chuong T., Morrissey J.H., Stucky G.D., University of Californi, Santa Barbara, US

Uncontrolled hemorrhage is a major cause of preventable death. Wound treatment focuses on using nanostructured oxide and clay-based materials to quicken clot formation. Internal injuries further complicate treatment due to inaccessibility. In response to severe [...]

Application of superparamagnetic nanoparticles for magnetically guided release of anti-cancer drug: An Ivvivo study on Rats

Choubey J., Swami M., Rani Durgawati Vishwavidyalya, Jabalpur, IN

By using appropriate magnetic parameters, 50-80% of the injected nanoparticles could be targeted, thus eliminating systemic distribution and subsequent toxicity of the entrapped agent. In this report we present data on the use of magnetic [...]

Nanoherbal antiseptic medicine/ bandage for effective and safe treatment of external wounds

Tahir L., Nazir R., Khan N., Pakistan Council Of Scientific and Industrial Research, PK

Use of different antibiotics and bactericides in treatment of wounds has resulted in several side effects together with development of resistant bacterial strains. The need is to develop safe and new route for the treatment [...]

‘Sink effect’ of dually-decorated nanoliposomes on Abeta clearance

Re F., Minniti S., Bana L., Masserini M., Re F., University Milano Bicocca, IT

Plaques containing beta-amyloid peptides are one of the hallmarks of Alzheimer’s disease (AD) and the reduction of Abeta is considered a primary therapeutic target. Recently, strategies have been employed to reduce Abeta brain levels and [...]

Poly-Vinyl Pyrrolidone (PVP)-coated Silver (Ag) Nanoparticles (Ag-PVP): a Potential to Regulate Chlamydia trachomatis Inflammation

Yilma A.N., Singh S.R., Dixit S., Hidat G.G., Dennis V.A., Alabama State University, US

Chlamydia trachomatis is an important cause of sexually transmitted infection that can manifest itself as either acute cervicitis, pelvic inflammatory disease, and more commonly as a chronic asymptomatic infection. Previously we reported Ag-PVP (5-10 nm) [...]

A better biomaterial for bone regeneration: type II collagen

Tsai Y-H, Taipei Medical University, TW

Type II collagen facilitates osteogenesis and suppresses adipogenesis simultaneously during early stage of MSC differentiation, mediated through the same signaling cascades. Type II collagen-coated plates enhanced BMSC mineralization better than did either non-coated or type [...]