Biomaterials – Page 72 – TechConnect Briefs

Engineering of efficient biocatalysts using nanostructured mesoporous silicate carriers

Szymanska K., Bryjak J., Jarzebski A.B., Institute of Chemical Engineering, Polish Academy of Science, PL

Immobilization of free enzymes/proteins on water-insoluble mesoporous silica (MS) supports is often applied to obtain efficient biocatalysts for various applications. Three methods were applied for enzyme bonding onto MS: (1) physical adsorption with subsequent crosslinking [...]

Studies of Hybrid Nano-Bio-System: Single-Walled Carbon Nanotubes and Hydrogenase

Svedruzic D., Blackburn J.L., McDonald T.J., Heben M.J., King P.W., National Renewable Energy Laboratory, US

We have examined changes in single-walled carbon nanotubes (SWNT) optical signals upon addition of recombinant [FeFe] hydrogenases from Clostridium acetobutylicum or Chlamydomonas reinhardtii. We found evidence that novel and stable charge-transfer complexes are formed only [...]

Subcellular fractionation in a fluidic microsystem

Paulus A., Posch A., Hausmann M., Blankenstein G., Duong T., Kentsch J., Angres B., Stoll D., Stelzle M., NMI Natural and Medical Sciences Institute, DE

The availability of an easy-to-use, reproducible method for subcellular fractionation would significantly promote qualitative and quantitative analysis of subcellular protein composition. A microfluidic system with integrated electrodes was designed and fabricated allowing for dielectrophoretic manipulation [...]

Synthesis and characterization of Hyaluronan – Gold Nanoparticles: A nanostructured material for biomedical applications

Ramis-Castelltort M., Querol J., Ojea I., Catalan Institute of Nanotechnology (ICN), ES

Hyaluronan (HA) is a glycosaminoglycan with a number of biological roles, such as being a key structural component of extracellular matrix and an important mediator in the leukocyte adhesion and migration. HA is ubiquitous in [...]

Investigating electrospun nanofibrous scaffold mechanical properties

Farboodmanesh S., Chen J., Pelealuw J.L., Cloutier D.E., University of Massachusetts-Lowell, US

There has been a considerable growth and development in electrospun nanofibers for research activity, as well as commercial fabrication over the past couple of decades. These continuous nanofibers are solution driven exclusively by an electric [...]

Modified AFM Probes for Nanoscale Biomolecular Recognition Studies

Johnson W.T., Agilent Technologies, US

Biomolecular interactions, which are responsible for many physiologically important processes, can be studied by molecular recognition force microscopy (MRFM). In MRFM, nanoNewton scale single molecule interactions are observed and quantified one by one as an [...]

Proton Uptake by Dormant Bacterial Spores

Kazakov S.V., Pace University, US

A dormant bacterial spore is regarded as a natural ionic reservoir, i.e. a system capable of changing the external pH or ionic strength by accumulating or releasing ions. In this work, we introduce a method [...]

The Study of the Nanocontact Imprint with Aminosilane

Shen F.Y., Chen J.H., Chen N.H., Lam K.Y., Chen J.H., Chen N.H., Huang F.S., National Tsing Hua University, TW

The purpose of this paper is to develop nano-contact imprint technology with simple process by using soft HSQ (hydrogen silsesquioxane) mold transfer aminosilane ink on HSQ and glass substrates with binding Glutraic dialdehyde (GA) and [...]

Enrichment of serum phosphopeptide by nanoparticles to identify cancer biomarker

Shah A., Sachdev V., Bharti A., Boston University Medical School, US

The role of kinases in transformation and cancer progression is established. We hypothesize that The role the specific phosphoproteins/phosphopeptides will be present in cancer patient serum as leak proteins and their isolation and identification will [...]

Functionalized Inorganic Nanostructures for Biomedical Applications

Bonroy K., Jans H., Jans K., Van de Broek B., Van Meerbergen B., Van Summeren A., Jans H., Jans K., Reekmans G., Van de Broek B., Van Meerbergen B., Van Summeren A., Van de Broek B., Van Meerbergen B., Van Summeren A., Huang C., Stakenborg T., Trekker J., Willems M., Bartic C., Verhaegen K., Borghs G., IMEC, BE

Nanomaterials differ significantly from other materials due to two factors: increased surface area and quantumsize effects. These factors can enhance properties such as reactivity, strength and physical characteristics. Due to these characteristics, the coupling of [...]