Sensors, MEMS, Electronics – Page 262

Characterization of a Solid State DNA Nanopore Sequencer using Multi-Scale (Nano-to-Device) Modeling

Jenkins J.W., Sengupta D., Sundaram S., CFD Research Corporation, US

The rapid convergence of nanotechnology and biotechnology has generated a need for design tools that can incorporate sufficiently detailed models of the nanoscale molecular phenomena with overarching transport and related effects in microfluidic devices. Currently, [...]

Scaling of Electroosmotic Flow and Ionic Conductivity in Nanochannels

Qiao R., Aluru N.R., Beckman Institute for Advanced Science and Technology, US

Electrokinetic transport is widely encountered in many nanofluidic systems, and understanding its scaling as a function of various operating conditions, e.g., bulk concentration, is important for establishing design rules and for exploring the design space. [...]

Multiscale Modeling of Nanoflows

Drazer G., Acrivos A., Khusid B., Koplik J., New Jersey Institute of Technology, US

Using molecular dynamics simulations, we identified in previous work a new adsorption phenomenon in which, for poorly wetting fluids, a suspended particle, initially moving along the center of the nanochannel, is adsorbed onto the tube [...]

Computational Analysis of On-line Coupled ITP-CE

Horner M., Fluent, Inc., US

Lab-on-a-chip technologies combine a sequence of chemical and/or biological analyses on a miniaturized platform to perform an analytical task or series of tasks. Lab-on-a-chip applications include chemical/biological agent detection, DNA sequencing/analysis, and drug discovery, to [...]

System Simulations of Complex Electrokinetic Passive Micromixers

Wang Y., Lin Q., Mukherjee T., Carnegie Mellon University, US

This paper presents a composable system simulation framework using an analog hardware description language implementing behavioral models for electrokinetic micromixers that are capable of accurately capturing the effects of mixer topology/geometry, flow ratio and material [...]

Applications of Topology Optimization in the Design of Micro- and Nanofluidic Systems

Okkels F., Olesen L.H., Bruus H., Technical University of Denmark, DK

The material distribution method in topology optimization was developed in the late 1980ies for stiffness design of mechanical structures, and only recently the first steps have been taken towards implementing the method in fluidics. Topology [...]

Flat Fluidics: Programmable On-Chip Networks for Biological and Chemical Applications

Wixforth A., University of Augsburg and Advalytix AG, DE

We present a novel approach towards the needs of a versatile microfluidic chip-based microfluidic system with unique properties and functionality. Like for microarrays and in contrast to many existing microfluidic technologies, the fluid handling is [...]

Design Paradigms and Methodologies for Microfluidics

Hardt S., Darmstadt University of Technology, DE

This paper reviews and compares different strategies for designing and building up microfluidic systems, with a special emphasis on the system aspect as opposed to single components capable of performing only special operations. An overwhelming [...]

Micro and Nano Fluidics Design and Phenomena

A Fiber-Optic Biosensor Based on Monooxygenases and Sol–Gel Entrapped Fluoresceinamine for Trichloroethene and Tetrachloroethene

Ryoo D., Kim Y., Jeun K., Wood T., Choi Y., Jeonju Univ., KR

Tetrachloroethene (a.k.a. perchloroethene, PCE) and trichloroethene (TCE) are the most frequently detected groundwater contaminants which are suspected to cause cancer in humans. Monitoring of these carcinogens suffers from high costs and inaccuracy caused by cumbersome [...]