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Sector: Medical & Biotech

Topology Trade-offs in the Synthesis of Chip-based Electrophoretic Separation Systems

Pfeiffer A.J., Mukherjee T., Hauan S., Carnegie Mellon University, US
Micro-scale electrophoretic separation systems provide a highly effective, versatile and inexpensive method for separating a wide variety of chemical components. Particularly useful applications include separation of biological molecules, chemical sensing, and mobile drub delivery systems. [...]

Simulation of a Polymer Drop in a Shear Field with Dissipative Particle Dynamics Method

Chen S., Phan-Thien N., Fan X.J., Khoo B.C., National University of Singapore, SG
In the present study, the dynamics of polymer drops in micro channel under both steady state and transient shear flow conditions are investigated using Dissipative Particle Dynamics method. The polymer drop is made from finitely [...]

Numerical Simulation of Microfluidic Flow Using a Combination of Micro and Macro Computational Techniques: Scaling Issues

Mautner T., SPAWAR Systems Center San Diego, US
Recent literature has demonstrated the possibilities of using configurable surfaces to enhance the flow of fluids in MEMS devices. Not only are surface properties important in fluid delivery, the inherent problems of mixing by diffusion [...]

Modelling and Optimization of Medical Test Strips Made From Plastics

Peters D., Bolte H., Laur R., University of Bremen, DE
Introduction In cooperation with industrial partners, a behavioural model for the microsystem ‚Medical Test Strips‘ has been created by the authors in order to decrease cost and effort in the design process. As there is [...]

Numerical Simulation of Field Amplified Sample Stacking in Microfluidic System

Feng J.J., Krishnamoorthy S., Sundaram S., Bhardwaj R., Santiago J.G., CFD Research Corporation, US
In this paper we developed a numerical simulation method that solves the transport phenomenon associated with sample stacking in microchip-based separation system. The model is based on thin double layer approximation where the electrostatic force [...]

Simulation and Optimization of Colloidal Micropumps

Liu D., Maxey M., Karniadakis G., Brown University, US
A fast algorithm for particulate microflows has been used to simulate the 3D micro-colloidal pumps tested in the experiments conducted by Terray et al. The Force-Coupling Method and a penalty method were implemented in a [...]

A Study on the Novel Type of Ferrofluid Magnetic Pipette

Ahn J.J., Oh J., Choi B., Sogang University, KR
This study was performed to design the novel type of ferrofluid magnetic pipette on a micro scale for the purpose of applications to delivery systems, which is the core device of Lab on a chip [...]

Modular Silicon Micropump

Johnson A.D., Martynov V., Gupta V., Menchaca L., TiNi Alloy Company, US
A new micropump mechanism has been created that consists of two silicon/silicon oxide dies with vias and dome-shaped membranes. The membranes are bonded face-to-face to form variable-volume domed liquid chambers. The membranes increase and decrease [...]

A Computational Model for Simulation of Electroosmotic Flow in Microsystem

Yao G.F., Flow Science Inc., US
Electroosmotic flow is created by applying an external electrical field on the electrical double layer (EDL) formed due to the interaction of an electrolyte solution with dielectric surfaces. This kind of flow plays an important [...]

A Simple Description of Turn-induced Transverse Field Dispersion in Micrlfluidic Channels for System-Level Design

Magargle R.M., Hoburg J.F., Mukherjee T., Carnegie Mellon University, US
This abstract shows a simple analytical model for turn-induced dispersion that captures an essential aspect of the transition field from uniform to circumferential that has been ignored in prior simple descriptions. The model applies directly [...]

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