Medical & Biotech – Page 180 – TechConnect Briefs

System Identification for Motion of Proteins Using an AFM-based Nanorobotic Manipulation

Park J., Kim B-K., Kim D-H., Kim B-K., Kim D-H., Lee K-I., Korea Institute of Science and Technology, KR

It is greatly important to understand the mechanics of AFM-based nanorobotic manipulation for efficient and reliable handling of nanoparticles. Robust motion control of an AFM-based nanorobotic manipulation is much challenging due to uncertain mechanics in [...]

Converging Technologies (NBIC)

Bainbridge W.S., National Science Foundation, US

The convergence of nanotechnology, biotechnology, information technology and cognitive science can greatly improve human performance over the next ten to twenty years. The chief areas of application include: expanding human cognition and communication, improving human [...]

A Fokker-Planck Approach For Modeling Integrated NanoBio Systems

Jenkins J.W., Sundaram S., CFD Research Corporation, US

Physics-based, high-fidelity simulations have emerged as indispensable tools in the design of complex, microfluidic devices (lab-on-chip). However, ab-initio analysis becomes increasingly complicated as the dimensions of the device approach nanoscales and molecular information/interactions must be [...]

Biologically Inspired Controls over Assembly of Crystalline Nanostructures

De Yoreo J.J., Orme C.A., Qiu R., Dove P.M., Lawrence Livermore National Laboratory, US

By utilizing small molecules and proteins to modulate crystal nucleation and growth, living organisms produce single nanocrystals and nanocrystal composites that exhibit control over the location, phase and crystallographic orientation of the nuclei, as well [...]

DNA base damage: A Car-Parrinello Molecular Dynamics Study of Guanine and Thymine with an OH Radical

Wu Y., Mundy C.J., Colvin M.E., Car R., Lawrence Livermore National Labs, US

Understanding the basic chemistry of radicals and DNA bases is an important step in characterizing the potential damage to DNA. The chemical level understanding of such damage has far reaching implications for radiation therapy, health [...]

Electrohydrodynamic Interactions of an AFM Tip and a Biological Membrane

Fan T.H., Fedorov A.G., Georgia Institute of Technology, US

In biological applications, AFM imaging needs to be performed in the natural (aqueous) living environment of the cell in order to observe molecular level interactions and biochemical processes in-situ in the electrolyte solution and to [...]

Bio Nano Systems and Chemistry

Layout Verification by Extraction for Micro Total Analysis Systems

Baidya B., Mukherjee T., Carnegie Mellon University, US

The increasing complexity of MicroTotalAnalysis Systems is leading to a growing need for verification tools for such designs. Numerical simulation of such designs are slow, memory consuming and practically impossible for large designs. Schematic-based simulation [...]

Quasi-static Motion of Bubbles in Microchannel Contractions

Jensen M.J., Goranovic G., Bruus H., Technical University of Denmark, DK

We present a thorough theoretical and computational study of bubble dynamics in icrofluidic channels with contractions. We investigate the effects of geometry and surface physics (friction and contact angle) on the behavior of incompressible bubbles, [...]

CFD-based Optimization of Gas/Liquid Microreactors with Droplet and Bubble Transport

Hardt S., Pennemann H., Jiang F., Institute of Microtechnology Mainz, DE

Microreactors offer unique opportunities for the control of process parameters unparalleled by macroscopic equipment. A new gas/liquid microreactor is proposed allowing for fast mass transfer and small concentration gradients as well as a very narrow [...]