Medical & Biotech – Page 159 – TechConnect Briefs

Effect of Length of Biotin Modified n-Alkanethiolates on the Formation of a Self-Assembled Streptavidin-Biotin Monolayer on a Gold Surface

Kim D.-J., Cho E.C., Koo K.-K., Sogang University, KR

The molecular recognition between streptavidin and biotin makes the streptavidin-biotin system very useful in a wide range of biotechnological applications. Currently, biotin-modified n-alkanethiolates have been extensively studied to create a wide variety of self-assembled monolayers [...]

A Novel Electrochemical Nitric Oxide Sensor: Aligned RuO2 Nanowires Deposited on Pt filament

Wang C.Y., Liu J., Piantadosi C.A., Allen B.W., Duke University, US

We fabricated a novel electrochemical NO sensor by depositing aligned ruthenium oxide (RuO2) nanowires on a fine Pt filament. This device exhibited a high current density and a low detection limit for NO in aqueous [...]

Electrochemical Detection of Single-Nucleotide Mismatches: Application of M-DNA

Abu-Irhayem E., Long Y-T., Sutherland T., Li C-Z, Kraatz H-B, Lee J.S., University of Saskatchewan, CA

The detection of a single-nucleotide mismatch in a 20 base pair duplex DNA, using Electrochemical Impedance Spectroscopy, is presented. Mismatched DNA monolayers on Au electrodes were studied as normal duplex DNA (B-DNA) and after conversion [...]

Multiwalled Carbon Nanotubes as Platforms for the Design of Biosensors

Mendoza E., Borowiak-Palen E., Sharpe K., de Silva S.G.M., Mureau N., Silva S.R.P, University of Surrey, UK

Carbon Nanotubes have unique properties such as chemical stability, good mechanical properties and high surface area that makes them ideal for the design of sensors. In this study, we present the use of Carbon Nanotube [...]

The Use of Quartz Crystal Microbalance in Cell Differentiation Detection

Shih C-J, Ke W-W, Lieu C-H, Industrial Technology Research Institute/Electronics Research & Service Organization, TW

We try to investigate whether the hematopoietic cell differentiation can be detected by Quartz Crystal Microbalance. Because certain hematopoietic transcription factors play a critical role in cell differentiation and lineage determination, they can be alternate [...]

Microcantilever Array Sensor for DNA and RNA Detection

Cherian S., Natesan M., Macis E., Cain R., Tedeschi L., Citti L., Palchetti I., Tombelli S., Raiteri R., University of Genova, IT

A microcantilever array platform is used for the detection of DNA hybridization and mRNA using selected immobilized oligonucleotides. Parallel detection on sixteen cantilevers are carried out simultaneously. The immobilization procedure and the results of the [...]

Signal Amplification of Surface Plasmon Resonance based on Gold Nanoparticle-Antibody Conjugate and its Application to Protein Array

Lee D-B, Lee W., Lee D-B, Lee W., Kim Y-W., Choi J.W., Sogang University, KR

Nanoparticles have offered many diverse capabilities in bioanalysis and biotechnological applications, due to the intrinsic properties of nanoparticle that is distinguished from bulk materials. The integration of nanoparticle, which exhibit unique electronic, photonic, and catalytic [...]

Sector: Medical & Biotech