Medical & Biotech – Page 131 – TechConnect Briefs

Selective Heating Characterization of Nanoplate Devices for Simultaneous Sensing of Multiple Biomolecule Species at Ultra-low Concentrations

Elibol O.H., Reddy_Jr. B., Bashir R., Purdue University, US

We propose a novel scheme for the en masse fabrication and selective functionalization of field effect silicon nanoplate devices to enable the ultrasensitive, simultaneous and label-free detection of multiple biomolecular species in real time. The [...]

In-Plane Transduction of Nanomechanical Microcantilever Motion To Enable Sensor Arrays

Nordin G.P., Kim S., Noh J., Qian Y., Brigham Young University, US

We have recently introduced a new microcantilever transduction mechanism that is designed to scale to large arrays on a single chip while maintaining a very compact form factor and high sensitivity. It is based on [...]

Diagnostics & Assays

Cerebral Oxygen Diffusion and Transport, at the Microscopic Level, and BOLD fMRI

Hadjistassou C.K., Moyle K., Ventikos Y., University of Oxford, UK

With the prospect of elucidating the Blood Oxygenation Level Dependent (BOLD) fMRI effect we consider cerebral oxygen transport at the microscopic scale. We concentrate on the transient response of a capillary-tissue system following brain activity. [...]

The binding site interactions between 7-chloro-tetracycline and the Tet Repressor

de Bruin P.H.S., Flores M.Z.S., Caetano E.W.S., Cavada B.S., Freire V.N., Universidade Federal do Ceará, BR

Tetracyclines are a class of broad spectrum antibiotics whose use has been limited by the emergence of bacterial resistance. The most common mechanism of resistance is regulated by the repressor protein, TetR. The structure of [...]

A Synchrotron X-ray Scattering Study on the Structure of Pepsin in Solution

Jin K.S., Jin S., Jin K.S., Jin S., Yoon J., Heo K., Kim J., Ree M., Pohang University of Science and Technology, KR

To understand the conformational behavior of a protein, it is necessary to define not only the structure of its native state but also that of various denatured states. Recent studies have revealed the biological significance [...]

Conditional Probabilistic Modeling of Carbohydrate Metabolism

Barjis I., Sierra M., New York City College of Technology, US

The ongoing processes of metabolic network are very complex, and consequently, difficult to understand and teach; furthermore, it is impossible to predict and analyze it when unpredictable changes are made. Because of the complexity of [...]

Molecular Synergy in the Nano-networks

Znamirowski L., Silesian University of Technology, PL

Technology heterogeneity in the products or object fabrication system, where the external control system usually is based on silicon technology, the interface e.g. transducers or robots represents mixed technology, and the controlled process another, leads [...]

Computational Modeling in Life Sciences

Analytical Model for Magnetic Particle Transport in a Magnetically Biased Microfluidic System

Furlani E.P., University at Buffalo, US

An analytical model is described for predicting the transport and capture of magnetic micro/nano-particles in a magnetophoretic microsystem that consists of an array of integrated soft-magnetic elements embedded beneath a microfluidic channel. The elements are [...]