Papers – Page 131 – TechConnect Briefs

A simple process for selective bio-functionalization of SU-8 surface for Lab-on-a-Chip applications

Srinivasan B., Chaurasia D., Vanjari S., Singh S., Indian Institute of Technology - Hyderabad, IN

SU-8 is a popular epoxy based negative photoresist developed by IBM. It has been widely used as structural material in Bio-MEMS and Lab-on-a-Chip devices due to its bio-compatible properties. SU-8 surface has hydrophobic nature. Often [...]

Determination of the bi-substrate kinetic coefficients for the beta-D-glucose- NAD-GDH enzymatic reaction

Berthier J., Cubizolles M., Laurent P., Pouteau P., Poher V., Cosnier M.L., CEA, FR

Colorimetric detection of glucose in sample liquids such as human plasma is made by using enzymatic reactions. In the multi reactional scheme, the first enzymatic reaction is determinant. Either glucose oxidase (GOX) or glucose dehydrogenase [...]

Zn(II)-Mediated Gold Nanosensors for Protein Phosphatase Assay

Lee J-O, Kim G.B., Kim Y.P., Kim G.B., Kim Y.P., Hanyang University, KR

Since gold nanoparticle (AuNP)-based colorimetric assays have been preferred for enzyme activity assay,[1] a few of attempts have been designed for the simple and rapid detection of PP activity. However, they still have drawbacks including [...]

Improving the sensitivity of Pedot:Pss modified gold electrode using gold and silver nanoparticles for Ganoderma boninense DNA detection

Dutse S.W., Yusof N.A., Ahmad H., Hussaini Adamu Federal Polytechnic, NG

The sensitivity of a designed electrochemical DNA biosensor was improved using gold and or silver nanoparticles. A gold electrode modified with a conductive nanocomposite of poly(3,4-ethylenedioxythiophen)–poly(styrenesulfonate) (Pedot-Pss) and gold or silver nanoparticles enhanced the conductivity [...]

SU-8 Based Flexure-FET Biosensor to Achieve Ultrasensitive Response

Chaurasiya D., Srinivasan B., Vanjari S., Singh S.G., Indian Institute of Technology, IN

This work presents SU-8 based Flexure-FET biosensor to achieve ultrasensitive response. Here, gate of FET is replaced with the fixed-fixed beam. Beam is biased near to pull-in instability (Vpi) and FET channel is biased in [...]

Cellular Delivery Modalities for Semiconductor Quantum Dots: A Comparative Analysis

Field L.D., Naval Research Lab/ University of Maryland College Park, US

Fluorescence continues to be one of the most useful tools employed by life scientists to visualize cellular processes. Semiconductor nanocrystals or quantum dots (QDs) have been demonstrated to be superior alternatives to traditional fluorophores (dyes [...]

Sensing voltage change across a lipid bilayer

Chen Y., Makinen A.J., O’Shaughnessy T.J., Efros A.L., Huston A., Susumu K., Stewart M.H., Delehanty J.B., Naval Research Laboratory, US

Developing nanoscale probes capable of real-time sensing and imaging of neuronal action potentials would be useful in understanding neuronal communication. However, current available tools for imaging action potentials lack either the spatial or temporal sensitivity [...]

From Nanogenomics and Structural-Functional Proteomics to Personalized Medicine for Oral Lichen Planus (OLP) as a Translational Model of Oral Cancer Usefull to Introduce an Industrial Technical Innovation

Nicolini C., Peshkova E., Bragazzi N., Fondazione ELBA Nicolini, US

Oral Lichen Planus (OLP) is a common chronic inflammatory disease, which involves the mucous membranes of the oral cavity, with an overall age-standardized prevalence of 1.27% (0.96% in men and 1.57% in women) as reported [...]

Microarray based Functional Nanoproteomics and Cancer

Nicolini C., Peshkova E., Fondazione ELBA Nicolini, US

Using NEBL proprietary “SNAP based Genes Expression” in conjuction with our proprietary “Submicron Arrays” (Anodic Porous Allumina and/or Kapton based Nanopores) , we use proprietary DNASER and Label Free Nanotechnologies to carry out : 1_Construction [...]

A Multifunctional Theranostic Nanoplatform for Image-Guided Surgery and Intraoperative Therapy

Taratula O., Schumann C., Duong T., Taylor K.L., Taratula O., Oregon State University, US

Currently, only optimal surgical resection of all disease sites can improve survival of ovarian cancer patients. Even with the best microsurgical techniques, however, palpation and visual inspection for malignant tissue identification can result in microscopic [...]