Numerical Modeling of Magnetic Field Flow Fractionation in Microchannels: A Two-fold Approach Using Particle Trajectories and Concentration

, ,
,

Keywords: , , , , ,

Submicronic paramagnetic particles are currently used for biological applications like medical diagnostic [1]. Recently modeling of displacement of such particles has seen new developments like the calculation of the trajectory of a particle [2], or the calculation of the concentration of a great number of such particles, at the same time, in a magnetic and hydrodynamic fields [3]. It is shown here that the two approaches – determinist and statistical – are consistent when applied to the calculation of a Magnetic Field-Flow Fractionation channel (MFFF) [4]: both numerical models predict similar convective patterns and the same accumulation location on the channel wall. Moreover, the application to a MFFF shows that submicronic paramagnetic particles can be separated by such methods depending on their size and magnetic susceptibility.

PDF of paper:


Journal: TechConnect Briefs
Volume: 1, Technical Proceedings of the 2001 International Conference on Modeling and Simulation of Microsystems
Published: March 19, 2001
Pages: 202 - 205
Industry sector: Sensors, MEMS, Electronics
Topic: Micro & Bio Fluidics, Lab-on-Chip
ISBN: 0-9708275-0-4