A proof of concept: a model of targeted stealth nanoparticles that are stable and biocompatible for RNA interference in vivo to macrophages

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Bringing together advances generated through the developing fields of bionanotechnology and gene therapy, and demonstrated through the ABCD model, we propose a biocompatible, stable, specific stealth lipoplex targeting macrophages, as proof of concept, which is to be developed into a novel disease modifying agent in the treatment of systemic autoimmune diseases such as rheumatoid arthritis

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Journal: TechConnect Briefs
Volume: 3, Nanotechnology 2010: Bio Sensors, Instruments, Medical, Environment and Energy
Published: June 21, 2010
Pages: 364 - 367
Industry sector: Medical & Biotech
Topics: Biomaterials, Materials for Drug & Gene Delivery
ISBN: 978-1-4398-3415-2