streptavidin – TechConnect Briefs

Aerosol manufacturing of plasmonic biosensors with silica coated nanosilver

Sotiriou G.A., Blattmann C.O., Pratsinis S.E., ETH Zürich, CH

Development of biosensors for medical applications is an on-going research field of great importance. In particular localized surface plasmon resonance (LSPR) biosensors show a high potential to detect analytes at low concentrations in biological fluids. [...]

Attenuated-Affinity Biotin Analogs for Catch-and-Release with Streptavidin

Corry S., Ying L-Q, Branchaud B., Life Technologies, US

The binding between streptavin and biotin, which is one of the strongest non-covalent interactions known in nature, is used ubiquitously in molecular biology. However, when a biotinylated molecule is captured for testing purposes and cannot [...]

Detection of Small Molecule-Protein Binding with Amorphous Silicon Nanostructures

Lund J., Mehta R., Parviz B., University of Washington, US

We present the fabrication and characterization of a nano-scale sensor made of amorphous silicon (a-Si) for electronic detection of small molecule –protein binding. The main component of the detector is a nano-scale a-Si semicircle with [...]

Effect of Length of Biotin Modified n-Alkanethiolates on the Formation of a Self-Assembled Streptavidin-Biotin Monolayer on a Gold Surface

Kim D.-J., Cho E.C., Koo K.-K., Sogang University, KR

The molecular recognition between streptavidin and biotin makes the streptavidin-biotin system very useful in a wide range of biotechnological applications. Currently, biotin-modified n-alkanethiolates have been extensively studied to create a wide variety of self-assembled monolayers [...]

Detection of DNA Hybridyzation with Impedance Amplifying Labels

Ma K-S, Madou M., Zhou H., Fischetti A., Zoval J., Madou M., University of California Irvine, US

Traditionally used nucleic acid analysis detection platforms rely on fluorescent or radioactive labels. Optical techniques require large and expensive equipment such as automated colorimetric and fluorimetric instruments that greatly increase the cost of the whole [...]