simulation – Page 9 – TechConnect Briefs

A Computational Model for the Design of ElectroWetting On Dielectric (EWOD) Systems

Bedekar A.S., Jenkins J.W., Sundaram S., CFD Research Corporation, US

Microfluidics has enabled the development of integrated lab-on-a-chip (LoC) devices for use in a clinical diagnostics, high throughput screening, drug discovery, biodefense and environmental monitoring. Although most microfluidic devices are based on continuous flow of [...]

Systems Biology Conceptual Modeling by Means of Discrete-event Simulation (DNA-RNA-Protein)

Yeol J.W., Barjis I., Barjis J., Barjis I., Barjis J., Berri S., Ryu Y., Polytechnic University, US

In this paper discrete-event simulation modeling technique is used to model and simulate biological processes. In particular, we study application of discrete-event simulation to model processes taking place in Glycolosis and capture dynamic behavior of [...]

A Multi-scale, Integrative Model of Cellular Electrophysiological Response Incorporating Intra/Extra-cellular Transport & Dynamics

Feng J.J., Krishnamoorthy S., Sundaram S., CFD Research Corporation, US

Spurred by the growing confluence of nano and bio technologies, several novel micro/nano platforms (see for example, whole cell patch clamp devices [1]) are emerging for the high-throughput and/or high-fidelity study of the electrophysiological response [...]

Modeling and Simulation of Carbohydrate Metabolism using Petri Net

Barjis I., Barjis J., Yoel J.W, Barjis I., Barjis J., Berri S., Ru Y.S., Polytechnic University, US

In this paper Petri net modeling technique is used to model and simulate biological processes. In particular, we study application of Petri nets to model processes taking place in Glycolosis and capture dynamic behavior of [...]

Simulation of Viral Gene Delivery

Dinh A.T., Mitragotri S., Theofanous T., university of california, santa barbara, US

Here we develop an integrative computational framework to model biophysical processes involved in viral gene delivery. The model uses reaction-diffusion-advection equations that describe intracellular trafficking in combination with kinetic equations that describe transcription and translation [...]

Modeling and Simulation of Multi-walled Carbon Nanotubes using Molecular Dynamics Simulation

Wong C.H., Liew K.M., He X.Q., Tan M.J., Meguid S.A., Nanyang Technological University, SG

Molecular dynamics simulation is performed on the buckling behavior of single and multi-walled carbon nanotubes under axial compression. Brenners second generation empirical potential is used to describe the many-body short range interatomic interactions for single-walled [...]

Silicon Nanostructures Patterned on SOI by AFM Lithography

Ionica I., Montès L., Ferraton S., Zimmermann J., Bouchiat V., Saminadayar L., IMEP-INPGrenoble, GF

The actual trends in microelectronics are the reduction of the dimensions and the search of new devices standing upon new phenomena as in the case of a Single Electron Transistor (SET) that is based on [...]

Kinetic Monte Carlo Modeling of Boron Diffusion in Si Crystalline Materials

Seo J., Hwang C-O, Kwon O., Kim K., Won T., School of Engineering, Inha University, KR

In this paper, we report a lattice-free kinetic Monte Carlo (KMC) result of boron diffusion at low temperatures 450o and 550o with vacancy + interstitialcy mechanism or vacancy + kick-out one with dilute self-interstitials (I) [...]

2D Quantum Mechanical Device Modeling and Simulation: Single and Multi-fin FinFET

Kim K., Kwon O., Seo J., Won T., Inha University, KR

A two-dimensional quantum mechanical modeling has been performed to simulate a nano-scale FinFET by obtaining the self-consistent solution of coupled Poisson and Schrödinger equations. Calculated current-voltage (I-V) curves are carefully compared with experimental data to [...]

Investigation of dsDNA Stretching Meso-mechanics using Finite Element Method

Yuan C.A., Chiang K.N., National Tsing Hua University, TW

A novel finite element model with equivalent meso-mechanics theory is proposed herein to simulate the dynamic structural transitions of the double strand DNA (dsDNA) under external loading. Moreover, the meso-mechanics of dsDNA molecules is then [...]