sequencing – TechConnect Briefs

Nanopore/electrode structures for single molecule biosensing

Albrecht T., Imperial College London, UK

In this contibution I will present some of our work on solid-state nanopores, the fabrication of nanopore/electrode structures and how these can be used for single-molecule biosensing applications (DNA, proteins etc.). Specifically, I will introduce [...]

Using Electron Tunneling for Direct Sequencing of DNA

Lund J., Dong J., Mehta R., Rahimi M., Ryan D., Parviz B.A., University of Washington, US

Genomic information has assumed a central role in the way biology in general and cell function in particular are understood today. Methods that can sequence DNA rapidly, accurately, and cost-effectively are needed in order to [...]

Assembly of DNA Rotaxanes for AFM Based DNA Sequencing

Spadola Q., Qamar S., Lin L., Lindsay S.M., Ashcroft B., Zhang P., Lindsay S.M., The Biodesign Institute at Arizona State University, US

The desire to sequence DNA is fueled by the knowledge that the information locked inside of genomes can help fields as varied as molecular medicine, bioarcheology, forensics, and environmental science. The challenge is to establish [...]