nanospheres – TechConnect Briefs

Self-Assembled Polystyrene Nanospheres for Plasmonic Enhancement in Biosensor Applications

Smith K., Norville C., Windham M., Dawson J.M., West Virginia University, US

The field of portable, point-of care biosensing has expanded in recent years to encompass a wide range of application areas, with detection of targets accomplished by a variety of techniques. Application-specific needs of further reduced [...]

Biomimetic Biphasic Nanocomposite Scaffold for Osteochondral Regeneration

Castro N.J., O’Brien C., Zhang L.G., The George Washington University, US

The current work focused on the development and evaluation of a novel biomimetic biphasic nanocomposite scaffold for osteochondral interfacial tissue engineering. Tissue-specific growth factor-encapsulated nanospheres were manufactured via a wet electrospray technique and incorporated within [...]

Preparation And Evaluation Of In Vitro Release Of Amphiphilic _-Cyclodextrin Or Pla Nanospheres Containing A Hydrophobic Drug

Lin S., Lahiani-Skiba M., Naouli N., Lahiani-Skiba M., Skiba M., Université de Rouen, FR

Mebendazole (MBZ) is an antihelmintic which belongs to group of benzimidazols. It is used for many intestinal diseases and for other diseases. But its low absorption, its high dosages caused side effects on gastro-intestinal track, [...]

Evaluation of the paromomycin loading characteristics in nanoprecipitated PLGA nanospheres

Kalimouttou S., Lahiani-Skiba M., Naouli N., LIN V.S., Lahiani-Skiba M., Skiba M., Université de Rouen, FR

The aim of this work was to optimize the preparation of poly(lactic-co-glycolic acid) (PLGA) nanoparticles loaded with paromomycin by a nanoprecipitation technique. PLGA was choosen because of its biodegradability and biocompatibility features. In order to [...]

From nanopores to nanoshells: The transformation of MCM-41 into ultrathin wall, hollow silica nanospheres

Ho W.Y., Yeung K.L., Hong Kong University of Science and Technology, HK

This work describes the preparation of ultra-small and ultra-thin hollow silica nanospheres from mesoporous MCM-41. The partially converted MCM-41, which retained the silhouette of the original MCM-41 particle, but is severely riddled with holes from [...]

Polymer Nanospheres for Improved Drug Delivery of Protein Therapeutics and Viral Antigens

Castor T.P., Aphios Corporation, US

Biologically adherent polymeric microsphere carriers have been shown to be effective in the oral delivery of proteins such as insulin and DNA plasmids. These microspheres are comprised of hydrophobic copolymers that appear to have a [...]

Parylene Polymers for Nanotechnology Applications

Kumar R., Greiner A., Specialty Coating Systems, US

During the past several years, Parylene polymers have been considered an integral part of micro devices by many biomedical engineering researchers as devices are made of Parylene through MEMs technology. In advancing Parylenes applications further [...]