nanoparticle – Page 11 – TechConnect Briefs

Modeling Aggregation and Size Distribution of Nanoparticles with Monte Carlo Simulation

Liu H., Surawanvijit S., Rallo R., Orkoulas G., Cohen Y., University of California, Los Angeles, US

The size distribution of the nanoparticles and their aggregates is crucial for predictions of the fate and transport of nanoparticles in the environment. A computational model was developed in the present work based on a [...]

Multi-Modal Superparamagnetic Nanoprobe: Harnessing Magnetic, Nuclear, and Optical Power for Diagnostic Imaging Applications

Bumb A., Regino C.A.S., Bernardo M., Dobson P.J., Choyke P., Brechbiel M.W., National Cancer Institute, US

Accurate characterization of the first draining sentinel lymph nodes in primary tumors is a challenging task where current methods rely on nodal size as the primary yardstick for differentiating benign from malignant nodes. Other parameters [...]

Nanoparticle size and shape evaluation using the TSOM optical microscopy method

Attota R., Silver R.M., Vladar A., NIST, US

We present a novel optical technique that produces nanometer dimensional measurement sensitivity using a conventional optical microscope, by analyzing through-focus scanning optical microscope (TSOM - pronounced as ‘tee-som’) images obtained at different focus positions. In [...]

Synthesis and characterization of FITC-aminated agarose as highly-fluorescent labeling agent

Zhang L., Huang J., Chu B., Tang S., Jinan University, CN

A new fluorescent agent, FITC labeling agarose is designed to determine whether it can act as an effective fluorescent labeling agent of cell or not. The degraded agarose reacted with 3-chloro-1, 2-epoxypropane in NaOH medium [...]

Biomedical Applications of Modified Carbon Glassy Electrode Sensor with Nanoparticles and Dendrimers

Leung S.W., Wang Y., Gu H., Lai J.C.K., Idaho State University, US

In our previous reports, we studied the development of biosensor platform that are capable of measuring biometabolites and environmental sensitive species, such as peroxide and nitrate/nitrate, to concentration in the order of ppb (parts per [...]

Label-free, Fluorescenece Detection of DNA Nanoparticle Scaffolds

Kell A.J., Tan S., Charlebois I., Boissinot M., Simard B., National Research Council, CA

We have developed a nanoparticle-based DNA biosensor that can detect unlabelled ssDNA with good sensitivity (picomolar concentrations). The biosensor makes use of the optical changes of a cationic polymer interacting with ssDNA versus that of [...]

Intermittent desolvation method to prepare size-controlled BSA nanoparticle

Paik S-Y-R, Nguyen H.H., Yang S.C., Che J., Ko S., Sejong university, KR

The development of standard method for nanoparticle preparation using food-grade materials is helpful for various nanotechnology-related applications for food product. In this study, bovine serum albumin (BSA) nanoparticles were prepared using a desolvation method. The [...]

PRINT® Nanoparticle Manufacturing Scaleup for Pharmaceutical Applications

Schorzman D.A., Liquidia Technologies, Inc., US

Nanotechnology research is still in its infancy, and while nanotechnology is widely seen as having huge potential, the pharmaceutical industry remains skeptical that success at the bench scale can successfully be translated into high volume [...]

Nanoparticle release from nano-containing product, introduction to an energetic approach

Gheerardyn L., Le Bihan O., Dore E., Morgeneyer M., INERIS, FR

The use of nanoparticles in manufactured products becomes more and more frequent and could lead to new potential risks for the workers, the consumers and the environment. This study focused on the R&D process of [...]

New method for the caracterization of abrasion-induced nanoparticle release into air from nanomaterials

Golanski L., Guiot A., Tardif F., CEA, FR

Nanotechnologies are emerging around the world. Nanoparticles are finding new industrial applications every day. Due to the variety of nanoparticles, toxicology studies will take time to establish the dangerousness of every kind of nanoparticle. Today [...]