nanofluidics – TechConnect Briefs

The Development of an Optofluidic Evanescent Field Sample Trapping and Loading Solution for Time Resolved Protein Crystallography Experiments

Diaz A.J., Docker P., Sparkes M.R., Kay J., Stuart D., Beale D. Axford J., ONeil W., Cordovez B., Diamond light Source, UK

X-ray crystallography is the leading technique for determining the atomic structure of biological molecules. The developers of this technique have maintained this position by continuously pushing the hardware and software boundaries such that data-collection from [...]

Nanoscale Flow Chip Platform For Laboratory Evaluation Of Enhanced Oil Recovery Materials

Engel M., Neumann R.F., Giro R., Bryant P.W., Steiner M.B., IBM Research Brazil, BR

We present a lab-on-chip platform for the experimental evaluation of Enhanced Oil Recovery [EOR] methods from the nanoscale to the scale of reservoir rock pore networks. We have employed semiconductor process technology to build lab-on-chip [...]

Nanofluidics: Wetting and Spreading Phenomena and Applications

Wasan D., Nikolov A., Illinois Institute of Technology, US

Suspensions of nanometer-sized particles in liquids (nanofluids) are used in a variety of technological applications and biological systems. For example, their spreading and adhesion behavior on solid surfaces can yield materials with desirable structural and [...]

Studies on Photothermal Effect in Nanofluidic Channel Toward Ultrasensitive Detection of Nonfluorescent Molecules Using Differential Interference Contrast Thermal Lens Microscope

Shimizu H., Mawatari K., Kitamori T., The University of Tokyo, JP

Absorption spectroscopy in nanofluidic channel was investigated for ultrasensitive detection of nonfluorescent molecules in nanospace. Recently, chemical analysis systems have been rapidly miniaturized from microspace to nanospace, which requires ultrasensitive detection of a broad range [...]

Interfacial effects and diffusion transport regimes in nanofluidic systems

Ziemys A., Milosevic M., Ferrari M., Kojic M., The Methodist Hospital Research Institute, US

Because the Peclet number is very small for nanofluidic systems, diffusion may be at least as important as the active mass transport. In nanoscale solid surfaces may alter fluid properties and diffusion at interface. Here, [...]

Static and Dynamic Properties of the Electrical Double Layer Near Amorphous Silica: Relevance for Device Design

Shi B., Shin Y.K., Zhang H., Hassanali A., Shin Y.K., Knight C., Singer S.J., Ohio State University, US

Amorphous silica (“glass”) is commonly used to fabricate micro- and nano-fluidic devices. Using an atomistic model, we have studied the static and dynamic properties of the electrical double layer near the water/amorphous silica interface. The [...]

Atomistic Simulations of Biomolecules at the Water‐Amorphous Silica Interface: Application to Peptides and DNA Oligomers

Shi B., Shin Y.K., Shin Y.K., Hassanali A., Singer S.J., Ohio State University, US

Realistic modeling of biomolecules near amorphous silica (“glass”), a material commonly used for biomedical device fabrication, is required for device design and evaluation. Our potential model, based on ab initio quantum chemical calculations, is designed [...]

Nano-plamsonics Sensing and Integration with Microfluidics for a Lab-on-chip Biosensor

Wei J.J., Rexius M., Kofke M., Wang Y., Singhal S., Waldeck D.H., CFD Research Corporation, US

Ordered arrays of nanostructures in metal films have been studied for practical miniaturization of SPR sensing and microfluidic integration. We report a nanostructure array that is designed to permit significantly enhanced Extraordinary Optical Transmission (EOT) [...]

Novel Low Temperature Fabrication Method for Label-Free Electronic Sensing of Biomolecules in Nanofluidic Channels with Integrated Electrodes

Wynne T., Huang X.T., Pennathur S., university of california, santa barbara, US

In this work, we demonstrate a surface micromachined fabrication approach for integrated addressable metal electrodes within centimeter-long nanofluidic channels using a low-temperature, xenon diflouride dry-release method for novel biosensing applications. The main contribution of this [...]

Molecular Dynamics Simulations of Flow over a Nano-cylinder in a Rectangular Nano-channel

Jabbarzadeh A., The University of Sydney, AU

This paper reports the molecular dynamics simulation results obtained for flow in a rectangular nano-channel of liquid alkanes around a nano-cylinder. The channel and cylinder have an explicit atomic structure and the liquid alkane (paraffin) [...]