microfluidics – Page 7 – TechConnect Briefs

Catching Mr. Big with the Small – ‘To Infinitesimal and Beyond”

Eastwood I., Authentix, US

In some parts of the world, the tax revenue from fuels is a big incentive for criminal syndicates to smuggle fuel and launder markers that are used to designate low tax fuels. These activities cost [...]

Catching Mr. Big with the Small – ‘To Infinitesimal and Beyond”

Eastwood I., Authentix, US

In some parts of the world, the tax revenue from fuels is a big incentive for criminal syndicates to smuggle fuel and launder markers that are used to designate low tax fuels. These activities cost [...]

A Rapid Prototyping and Mass-Production Platform of Microfluidic Devices

Craig Kung P., Kung Y.L., Holcombe D., Grace R.H., Ungelenk G., Piechotka E., Seiferth W., Optotrack, Inc., US

Microfluidic chips, disposable biosensors, and micro-optical devices have been primarily manufactured from silicon- or glass-based substrates for years. This approach involves sophisticated production tools, tedious development processes, and clean-room conditions. Given today’s fierce competition in [...]

Microfluidic Valve-Controllable Magnetic Bead Receptacle: A Novel Platform for DNA Sequencing

Esfandyarpour H., Davis R.W., Stanford Genome Technology Center, US

In this paper, a novel and effective microfluidic platform for DNA Sequencing, particularly for sequencing-by-synthesis methods such as Pyrosequencing, based on valve-controllable PDMS channel system contains micrometer magnetic beads . Additionally, the proposed picoliter micofluidic [...]

Fabrication and Application in Microfluidics of Novel Transparent Preceramic Polymer Derived Glass Microcannels and Substrates

Kim D-P, Park J.H., Perumal J., Chungnam National University, KR

Generally, glass-based microfluidics with the chemical inertness and thermal stability have widely used, while plastics including PDMS have showed their convenience in fabricating microfluidic devices. Therefore, one can simply anticipate that it must be desirable [...]

Control of Micro-Fluidic Flow using 3D Features

Bullock L.E., Robinson A.E., University of Massachusetts Dartmouth, US

Lab-on-a-Chip sensors require precise control and mixing of samples, reagents and buffers. This paper will present new techniques for using Excimer Laser, micro-machined, three-dimensional (3D) channel and well features to pump and control fluids in [...]

Using epoxy resin to fabricate a master for microfluidic devices in poly(dimethylsiloxane)

Pan Y-J, Yang R-J, National Cheng Kung University, TW

This paper presents two methods for the production of UV epoxy resin masters for the replication of PDMS-based microfluidic chips. The epoxy resin master can be either fabricated by using a negative glass template which [...]

Simulation on biological cell transport in the microfluidic devices

Kim M.C., Wang Z.H., Lam R.H.W., Thorsen T., Massachusetts Institute of Technology, US

We have developed a Bio-Particle (BP) simulation technique for the general particle movement in Lab-On-A-Chip devices. This has also been validated with experiments on biological cells (3T3 cell; diameter 10 μm). The cell motion under [...]

Droplet-based Segregation and Extraction of Concentrated Samples

Buie C.R., Buckley P., Hamilton J., Ness K.D., Rose K.A., Lawrence Livermore National Laboratory, US

Incorporating microfluidic-based technologies into bio-analytical instruments has many benefits including reduced sample consumption, faster response times, and improved sensitivity. To achieve these benefits, microfluidic analysis often requires sample concentration and separation techniques, e.g., isotachophoresis or [...]

Multifunctional Microvalves Control by Optical Illumination on Nanoheaters and its Application in Centrifugal Microfluidic Devices

Park J.M., Cho Y-K, Lee B-S, Lee J-G, Lee B-S, Lee J-G, Ko C., Samsung Advanced Institute of Technology, KR

We report ultrafast control of phase-change based microvalves utilizing nanoheaters; ferronanoparticles dispersed in paraffin wax, and heating by optical illumination using a 808 nm laser diode. High speed camera images showed that the actual response [...]