microfluidic – Page 2 – TechConnect Briefs

Microfluidic Platforms with Micro- and Nanopore Membranes and in situ Formation of Lipid Bilayer in the Microfluidic Platform

Choi J., Kim N., Park S., Louisiana State University, US

Artificial lipid bilayer membranes have come into the spotlight as topics of fundamental properties of biomaterials, targets for drug discovery and safety screening, and analytic platforms for characterization and orientation discrimination of polynucleotide molecules. Lipid [...]

A capillary effect based microfluidic system for high throughput screening of yeast cells

Mirzaei M., Juncker D., McGill University, CA

Microfluidic systems have been developed and used for high throughput cell-based assays successfully. However, these systems require complicated peripherals and a computer to control the flow, which limits their adoption by biologists. Here, we propose [...]

Lateral-Driven Continuous Dielectrophoretic Separation Technology for Blood Cells suspended in a Highly Conductive Medium

Seo J., Jung J., Jung Y., Han K-H, Han S-I., Han K-H, Han S-I., Jung J., Jung Y., Bruno Frazier A., Inje University, KR

This paper presents lateral-driven continuous dielectrophoretic (DEP) microseparator for separating red and white blood cells suspended in a highly conductive dilute whole blood. The DEP microseparators enable the separation of blood cells with continuous operation [...]

GRAVI-Chip: Automation of Microfluics Affinity Assay based on Magnetic Nanoparticle

Rossier J.S., Baranek S., Morier P., Vulliet F., Vollet C., Reymond F., DiagnoSwiss SA, CH

An automated nanoparticle based microfluidic platform called GRAVI™ will be presented here as a novel benchtop robotised system for fast and automated ELISA analysis in low volumes. This system can handle samples and reagents from [...]

Micrwave based microfluidic sensor

Tanbakuchi H., Bynum M., Brennen R., Whitener M., Agilent Technologies, US

SPR ( surface Plasmon Resonance) is an non destructive sensor capable of measuring the changes in refractive index above the gold surface (~300 nm) .The advantage of the SPR is in its capability of looking [...]

Magnetically Controlled Valve for Flow Manipulation in Polymeric Microfluidic Devices

Gaspar A., Piyasena M.E., Gomez F.A., California State University Los Angeles, US

Microfluidic devices (MDs) have emerged as novel analytical tools in many areas of science and industry. Their inherent qualities such as low power requirements, low sample consumption, rapid and parallel analysis, and automation provides unique [...]

A Microfluidic Mixer for Chaotic Mixing of Magnetic Particles

Zolgharni M., Azimi S.M., Bahmanyar M.R., Balachandran W., Brunel University, UK

Magnetic isolation of specific biological entities through utilizing super-paramagnetic micro-particles has been of great interest in both bench-top and microfluidic platforms. Since the magnetic particles and target entities are suspended in separate fluids, prior to [...]

Development of Immunoassay Microfluidic Chip Using Serial-flow Method

Hsieh J., Yin H-L, Huang T-T, Huang Y-C, Hsu H-H, Lin Y-S, Huang T-T, Huang Y-C, Instrument Technology Research Center, TW

A serial-type microfluidic chip toward immunoassay-on-chip is reported. The presented chip contains no active microvalves and micropumps, rendering its low cost and disposability. Due to the serial flowing of fluids, minimal control effort is required. [...]

Quantitative measurements of the strength of adhesion of human neutrophils to a substratum in a microfludic device: A novel inflammation diagnostic tool

Gutierrez E., Groisman A., University of California San Diego, US

We describe a quantitative assay of the strength of adhesion of activated and non-activated human neutrophils to a substratum, which is carried out in a custom-made microfluidic device. The strength of adhesion is quantified by [...]

Porous filter with spatially graded response

Krause K.M., Hawkeye M., Brett M., University of Alberta, CA

Glancing Angle Deposition (GLAD) has become a common technique for producing thin porous films with various structural features. In the current work, we have further modified GLAD in order to create porous structures that have [...]